Revealing the Mechanistic Pathway of Cholinergic inhibition of Alzheimer ’s disease by Donepezil: A Metadynamics Simulation Study

Phys. Chem. Chem. Phys., 2019, Accepted Manuscript DOI: 10.1039/C9CP02613D, PaperShibaji Ghosh, Kalyanashis Jana, Bishwajit Ganguly Donepezil, an acetylcholinesterase inhibitor, is an approved drug for the symptomatic treatment of Alzheimer ’s disease (AD). The mechanistic pathway for the inhibition mechanism of acetylcholinesterase (AChE) by donepezil is not... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Phys. Chem. Chem. Phys. latest articles - May 22, 2019 Category: Chemistry Authors: Shibaji Ghosh Source Type: research