Establishing a Link Between Mitochondrial Dysfunction and Late-Life Depression

Psychiatric disorders, in general, and depression, in particular, appear to be the consequence of multiple interacting biological factors. These factors may be apparent not only in brain, but also in peripheral tissues. Considering that brain function is difficult to study in life, there is a long history of attempts, as in the work of Brown et al.1 in the current issue of the American Journal of Geriatric Oncology, to find peripheral measures of function that might be correlated with brain abnormalities that underlie depression or other psychiatric conditions.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Invited Perspective Source Type: research