< b > < i > Staphylococcus epidermidis < /i > < /b > : A Potential New Player in the Physiopathology of Acne?

Background:Cutibacterium acnes has been identified as one of the main triggers of acne. However, increasing knowledge of the human skin microbiome raises questions about the role of other skin commensals, such asStaphylococcus epidermidis, in the physiopathology of this skin disease.Summary: This review provides an overview of current knowledge of the potential role ofS. epidermidis in the physiopathology of acne. Recent research indicates that acne might be the result of an unbalanced equilibrium betweenC. acnes andS. epidermidis,according to dedicated interactions. Current treatments act onC. acnesonly. Other treatment options may be considered, such as probiotics derived fromS. epidermidis to restore the naturally balanced microbiota or through targeting the regulation of the host ’s AMP mediators.Key Messages: Research seems to confirm the beneficial role ofS. epidermidis in acne by limitingC. acnes over-colonisation and inflammation.Dermatology

Source: Dermatology - May 21, 2019 Category: Dermatology Source Type: research