VicTORia: a randomised phase II study to compare vinorelbine in combination with the mTOR inhibitor everolimus versus vinorelbine monotherapy for second-line chemotherapy in advanced HER2-negative breast cancer

ConclusionAlthough well tolerated, the efficacy of everolimus and vinorelbine combination therapy was not superior to vinorelbine monotherapy. There was no correlation between PI3  K mutational status and efficacy.EudracCT No 2011-001024-38, ClinicalTrials.gov No NCT01520103
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research