Bone scan index as metastatic bone disease quantifier and predictor of radium-223-dichloride biochemical response

Conclusion BSI is a useful asset in stratification of patients with metastatic bone disease. It may also have a place in prediction of biochemical response.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: ORIGINAL ARTICLES Source Type: research

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Conclusion: The biopsy protocol that included six end-fire anterior cores did not detect more cancer and was associated with more complications. PMID: 31204873 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Urology - Category: Urology & Nephrology Tags: Scand J Urol Source Type: research
Conclusions: PCa patients with MSCC have a poor prognosis. Most likely reflecting differences in tumor burden, preserved gait function following radiotherapy is associated with better prognosis. Further prospective studies are required to confirm this association. PMID: 31204549 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Urology - Category: Urology & Nephrology Tags: Scand J Urol Source Type: research
ConclusionTracer biodistribution was not significantly impacted by normal tissue expression of PSCA. [89Zr]A2cDb immuno-PET yielded high tumor-to-blood ratio at early time points. Rapid renal clearance of the 50  kDa tracer resulted in an unobstructed view of the pelvic region at 20 h postinjection that would allow the detection of cancer in the prostate.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research
ConclusionsRadium-223 was generally well tolerated and there were no safety concerns. The adverseevents were mild and manageable. A decline in serum alkaline phosphatase was more frequent than a decline in the prostate-specific antigen. Monitoring changes in serum alkaline phosphatase dynamics may be useful.ResumenEl dicloruro de Ra223 es un radiofármaco emisor alfa que prolonga la supervivencia global en pacientes con cáncer de próstata resistente a la castración y metástasis óseas sintomáticas. Presentamos un análisis retrospectivo de 68 pacientes tratados.Mé...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
Conclusions: Early assessment of PSA after surgery is important for predicting radiographic progression in node-positive prostate cancer patients. Risk stratification based on the early PSA value after surgery would be helpful to identify patients who may benefit from early adjuvant therapies.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
The purpose of this study was to evaluate the imaging properties of hepatic metastases in 68Ga-PSMA positron emission tomography (PET) in patients with prostate cancer (PC).
Source: Cancer Imaging - Category: Radiology Authors: Tags: Research article Source Type: research
Researchers are investigating if men could benefit from a one-off scan to check their risk of prostate cancer.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
The magnetic resonance imaging (MRI) scan has already been offered to 450 men in UK, with another 350 set to be screened in London this summer as part of University College trial.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Simple scans ‘could revolutionise the way that we diagnose disease’, says professorHundreds of men will be given MRI scans in a groundbreaking clinical trial that scientists say could transform screening for prostate cancer.The £5m trial, which begins in August, is pioneering a simple, 10-minute scan that scientists hope could provide the first reliable method for identifying dangerous tumours in the general population.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Prostate cancer Society Cancer research Health Medical research Science UK news Source Type: news
Objectives The aims of this study were to assess the discriminative performance of quantitative multiparametric magnetic resonance imaging (mpMRI) between prostate cancer and noncancer tissues and between tumor grade groups (GGs) in a multicenter, single-vendor study, and to investigate to what extent site-specific differences affect variations in mpMRI parameters. Materials and Methods Fifty patients with biopsy-proven prostate cancer from 5 institutions underwent a standardized preoperative mpMRI protocol. Based on the evaluation of whole-mount histopathology sections, regions of interest were placed on axial T2-wei...
Source: Investigative Radiology - Category: Radiology Tags: Original Articles Source Type: research
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