Neurosurgical Resident Exposure to Pediatric Neurosurgery: An Analysis of Resident Case Logs

Conclusion: Neurosurgical residents graduating from 2013 to 2017 reported significantly higher volumes of pediatric neurosurgery cases than the standards set for by the ACGME. During this time, there was also a significant trend of increasing cases logged as the lead resident surgeon, suggesting more involvement in the critical portions of pediatric cases. There was also a significant, but not clinically impactful, decrease in pediatric case volumes during this time. However, the overall data indicate that residents are continuing to gain valuable pediatric experience during residency training.Pediatr Neurosurg
Source: Pediatric Neurosurgery - Category: Neurosurgery Source Type: research

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Today, we got called on a patient in the ICU who recently had a new brain mass removed surgically. The specimen came back positive for an aggressive brain tumor known as glioblastoma multiforme. We discussed his diagnosis and prognosis with him at bedside alone, with his wife and daughter on speakerphone given visitor restrictions due […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions COVID-19 coronavirus Infectious Disease Oncology/Hematology Source Type: blogs
Authors: Szmuda T, Ali S, Słoniewski P Abstract BACKGROUND: Fluorescence-guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) his proven to assist neurosurgeons to achieve a more complete brain tumour resection. However, 5-ALA-guided surgery is limited since it is often difficult to distinguish the colour difference between the resected areas of malignant brain tumours from their background. Our aim was to evaluate which colour difference formula was the most optimal to distinguish between malignant brain tumors from the background healthy tissue using 5-ALA fluorescence. MATERIALS AND METHODS: 37 patients ...
Source: Folia Morphologica - Category: Anatomy Tags: Folia Morphol (Warsz) Source Type: research
AbstractGlioblastoma is the most common aggressive primary brain tumor. Standard care includes maximal safe surgical resection, radiation, and chemotherapy with temozolomide. However, the impact of this therapeutic approach on patient survival is disappointing and poor outcomes are frequently observed. Therefore, new therapeutic targets are needed to treat this potentially deadly tumor. Aurora kinases are one of today ’s most sought-after classes of therapeutic targets to glioblastoma therapy. They are a family of proteins composed of three members: Aurora-A, Aurora-B, and Aurora-C that play different roles in the ce...
Source: Journal of Molecular Medicine - Category: Molecular Biology Source Type: research
CONCLUSIONS: This work demonstrated the feasibility of using sCT generated with a GAN-based deep learning method for MRI-only treatment planning of patients with brain tumor in intensity-modulated proton therapy. PMID: 32216098 [PubMed - as supplied by publisher]
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Tags: J Appl Clin Med Phys Source Type: research
ConclusionsHere, we highlight INSMI expression, as well as its diagnostic significance and use as a therapeutic target in various neuroendocrine tumors. Targeting signaling pathways or gene expression alterations associated with INSM1 expression may be instrumental for the design of novel therapeutic strategies for neuroendocrine tumors.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research
A machine learning model developed by Yale ’s Dr. Murat Günel makes predictions to help doctors diagnose the stage of brain cancers faster and more accurately.
Source: Yale Science and Health News - Category: Universities & Medical Training Source Type: news
Conclusion: Although cases of metastatic intradural extramedullary spinal tumors from ovarian cancer are extremely rare, their possibility should be considered in the differential diagnosis. A history of brain metastases and enhancement on T1-weighted MRI were helpful for making an accurate diagnosis. PMID: 32202486 [PubMed - as supplied by publisher]
Source: Journal of Spinal Cord Medicine - Category: Orthopaedics Tags: J Spinal Cord Med Source Type: research
Gliomas are complex and heterogeneous brain tumors with poor prognosis. Glioma cells can communicate with their surroundings to create a tumor-permissive microenvironment. Exosomes represent a new means of int...
Source: Molecular Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
ConclusionsThese findings point to a novel immunologic mechanism underlying the interaction between radiotherapy and immunotherapy. They also provide the basis for clinical investigation of immunogenic dose radiation in combination with immune checkpoint blockade as a potential treatment approach for newly diagnosed high grade gliomas.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
Abstract Intracranial myxoid mesenchymal tumors harboringEWSR1 fusions withCREB transcriptional factor gene families were recently described in several case reports and a few case series and this tumor closely resembles the myxoid variant of angiomatoid fibrous histiocytoma. We herein present an intracranial mesenchymal myxoid tumor arising in the third ventricle of a middle-aged woman. The tumor displayed prominent myxoid features consisting of mildly atypical oval to round cells, arranged in reticular and cord-like structures, with starburst-like amianthoid fibers, whereas it lacked pseudoangiomatoid spaces, pseudocaps...
Source: Brain Tumor Pathology - Category: Neurology Source Type: research
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