Application value of hypersensitive C-reactive protein, lactic acid and myoglobin in the combined detection of myocarditis.

Application value of hypersensitive C-reactive protein, lactic acid and myoglobin in the combined detection of myocarditis. Exp Ther Med. 2019 Jun;17(6):4471-4476 Authors: Liu Y, Huang X, Liu Y, Li D, Zhang J, Yang L Abstract Application value of hypersensitive C-reactive protein (hs-CRP), blood lactic acid (LAC) and myoglobin (Mb) in the combined detection of myocarditis was explored. A total of 107 patients with suspected myocarditis treated in The Second Nanning People's Hospital from January 2015 to December 2017 were retrospectively analyzed, of whom 81 patients diagnosed with myocarditis were enrolled into the research group, and 26 non-myocarditis individuals were enrolled into the control group. Fasting venous blood was drawn from all patients to detect the hs-CRP, LAC and Mb, and their levels were compared and analyzed between the two groups. Moreover, the coincidence rate, sensitivity and specificity of single detection and combined detection by hs-CRP, LAC and Mb in the diagnosis of myocarditis were compared and analyzed. There were no significant differences in the sex, age, smoking status, alcohol consumption, chest distress, palpitation, angina and dyspnea between the two groups (P>0.05), proving that patients in both groups were comparable. The levels of hs-CRP, LAC and Mb in the research group were significantly higher than those in the control group, displaying statistically significant differences (P
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research

Related Links:

A 30-something y.o. male with PMH significant for anxiety, asthma, and alcohol use disorder presented with chest pain x 1 week.  Patient thinks he has an asthma flare, with wheezing. He subsequently developed fevers and chills, and then left-sided chest pain associated with a cough. His breathing and infectious sx then improved. Today, however, he developed constant chest pain radiating into left arm around 1345. He states the pain is improving now. He had associated " swimmy, head rush, " which is no longer present. He denies associated shortness of breath, sweating, numbness, tingling. Onset of pain was wh...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
ConclusionsPPA2 gene plays a significant role in inherited infant dilated cardiomyopathies. According to the genotype, sudden death can happen very early in the childhood or might be triggered with alcohol absorption or common viral illness. PPA2 should be systematically added in the currently used cardiomyopathy genes panels but also in SUDI's since cardiac manifestations can be extremely acute especially in neonates.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Publication date: January 2019Source: Archives of Cardiovascular Diseases Supplements, Volume 11, Issue 1Author(s): L. Fauchier, A. Bisson, N. Clementy, B. Pierre, C. André, D. Angoulvant, D. Babuty, GYH. LipBackgroundAtrial fibrillation (AF) may be related to acute, temporary causes such as alcohol use, myocardial ischemia, myocarditis, hyperthyroidism, etc. It remains unclear whether antithrombotic management should be different in this setting after resolution of the episode.PurposeOur objective was to describe the outcomes in patients with such a temporary cause of AF (TCAF), and to compare the specific subgroup...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionsPPA2 gene plays a significant role in inherited infant dilated cardiomyopathies. According to the genotype, sudden death can happen very early in the childhood or might be triggered with alcohol absorption or common viral illness. PPA2 should be systematically added in the currently used cardiomyopathy genes panels but also in SUDI's since cardiac manifestations can be extremely acute especially in neonates.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
We present a 59-year old black male with history of type-1 diabetes and alcohol abuse. Patient became critically ill after a 5-day period of burning throat discomfort. On arrival patient was lethargic, in cardiogenic shock with a blood pressure of 81/47mmHg. Immediate diagnoses included diabetic ketoacidosis, acute renal failure, and possible septic shock. He was intubated, resuscitated with intravenous fluids, maintained on three inotropic agents, and given empiric wide spectrum antibiotics. An ECG showed a new ST elevation MI and an echocardiogram showed severe LV dysfunction.
Source: Cardiovascular Revascularization Medicine - Category: Cardiology Authors: Source Type: research
Publication date: Available online 10 February 2017 Source:The Lancet Author(s): Robert G Weintraub, Christopher Semsarian, Peter Macdonald Dilated cardiomyopathy is defined by the presence of left ventricular dilatation and contractile dysfunction. Genetic mutations involving genes that encode cytoskeletal, sarcomere, and nuclear envelope proteins, among others, account for up to 35% of cases. Acquired causes include myocarditis and exposure to alcohol, drugs and toxins, and metabolic and endocrine disturbances. The most common presenting symptoms relate to congestive heart failure, but can also include circulatory colla...
Source: The Lancet - Category: Journals (General) Source Type: research
Dilated cardiomyopathy is defined by the presence of left ventricular dilatation and contractile dysfunction. Genetic mutations involving genes that encode cytoskeletal, sarcomere, and nuclear envelope proteins, among others, account for up to 35% of cases. Acquired causes include myocarditis and exposure to alcohol, drugs and toxins, and metabolic and endocrine disturbances. The most common presenting symptoms relate to congestive heart failure, but can also include circulatory collapse, arrhythmias, and thromboembolic events.
Source: LANCET - Category: General Medicine Authors: Tags: Seminar Source Type: research
Authors: Maisch B Abstract The individual amount of alcohol consumed acutely or chronically decides on harm or benefit to a person's health. Available data suggest that one to two drinks in men and one drink in women will benefit the cardiovascular system over time, one drink being 17.6 ml 100 % alcohol. Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke. More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites. Histo...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Multiple reports of toxic myocarditis from inhalant abuse have been reported. We now report the case of a 23-year-old man found to have toxic myocarditis from inhalation of a hydrocarbon. The diagnosis was made by means of cardiac magnetic resonance imagin...
Source: SafetyLit - Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Flavonoids are frequently used as dietary supplements in the absence of research evidence regarding health benefits or toxicity. Furthermore, ingested doses could far exceed those received from diet in the course of normal living. Some flavonoids exhibit binding to estrogen receptors (ERs) with consequential vigilance by regulatory authorities at the U.S. EPA and FDA. Regulatory authorities must consider both beneficial claims and potential adverse effects, warranting the increases in research that has spanned almost two decades. Here, we report pathway enrichment of 14 targets from the Comparative Toxicogenomics Database ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
More News: Alcoholism | General Medicine | Hospitals | Myocarditis | Smokers | Statistics