A Systematic Review of Systemic Cobaltism After Wear or Corrosion of Chrome-Cobalt Hip Implants

Objectives We sought to synthesize data on systemic arthroprosthetic cobaltism, a recently described syndrome that results from wear or corrosion of chrome-cobalt hip components. Methods We conducted a systematic literature review to identify all reported cases of systemic arthroprosthetic cobaltism. To assess the epidemiologic link between blood cobalt levels (B[Co]), we developed a symptom scoring tool that evaluated 9 different symptom categories and a category of medical utilization. Results We identified 25 patients reported between 2001 and 2014 with a substantial increase in case reports over the past 3 years. Symptoms were diverse and involved the hip (84%), cardiovascular system (60%), audiovestibular system (52%), peripheral motor-sensory system (48%), thyroid (48%), psychological functioning (32%), visual system (32%), and the hematological, oncological, or immune system (20%). The mean latency from implantation to presentation or revision was 41 months (range, 9–99 months). The mean B[Co] was 324 μg/L and 4 patients had levels less than 20 μg/L. The B[Co] but not blood chromium level was highly associated with a quantitative measure of overall symptom severity (r2, 0.81; P
Source: Journal of Patient Safety - Category: Health Management Tags: Review Article Source Type: research

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Publication date: Available online 17 July 2019Source: Journal of Integrative MedicineAuthor(s): Pierre Watcho, Ismaelle Rosine Mpeck, Patrick Brice Defo Deeh, Modeste W.eu-Nya, Esther Ngadjui, Georges Romeo Fozin Bonsou, Pierre Kamtchouing, Albert KamanyiAbstractObjectiveCyclophosphamide (CP) is commonly used to treat some cancers, but its clinical efficacy is also linked with testicular toxicity. We investigated the effects of aqueous extract (AE) and methanolic extract (ME) of Helichrysum odoratissimum for reducing CP-induced reproductive toxicity in male rats.MethodsIn addition to a normal control (group 1), drugs or v...
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
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Source: World Journal of Acupuncture Moxibustion - Category: Complementary Medicine Source Type: research
ConclusionsThe therapeutic effect of acupuncture and moxibustion by soothing liver and regulating mind can obviously improve the quality of life of depression elders.
Source: World Journal of Acupuncture Moxibustion - Category: Complementary Medicine Source Type: research
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Source: Journal of the Saudi Heart Association - Category: Cardiology Source Type: research
Publication date: Available online 17 July 2019Source: Global HeartAuthor(s): Jessica Ying-Yi Xie, Matthew R. Solomons, Mahmood Ahmad
Source: Global Heart - Category: Cardiology Source Type: research
Publication date: Available online 18 July 2019Source: American Heart JournalAuthor(s): Nwora Lance Okeke, Allison R. Webel, Hayden B. Bosworth, Angela Aifa, Gerald S. Bloomfield, Emily Choi, Sarah Gonzales, Sarah Hale, Corrilynn O. Hileman, Virginia Kidwell, Charles Muiruri, Megan Oakes, Julie Schexnayder, Valerie Smith, Rajesh Vedanthan, Chris T. Longenecker
Source: American Heart Journal - Category: Cardiology Source Type: research
Conclusion: Experiences of being sexually harassed correlate among adolescents with high social anxiety but also with high self-esteem. Sexual harassment among adolescents may partly be explained as inept ways of showing interest, but it may nevertheless have detrimental effects on the well-being of the those subjected to it. PMID: 31311376 [PubMed - as supplied by publisher]
Source: Nordic Journal of Psychiatry - Category: Psychiatry Tags: Nord J Psychiatry Source Type: research
Publication date: Available online 17 July 2019Source: Journal of Geriatric OncologyAuthor(s): Mina S. Sedrak, Daneng Li, Louise C. Walter, Karen Mustian, Kevin P. High, Beverly Canin, Supriya G. Mohile, William Dale, Can-Lan Sun
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 17 July 2019Source: Journal of Geriatric OncologyAuthor(s): Melisa L. Wong, Stuart M. Lichtman, Gary R. Morrow, John Simmons, Tomma Hargraves, Cary P. Gross, Jennifer L. Lund, Lisa M. Lowenstein, Louise C. Walter, Cara L. McDermott, Supriya G. Mohile, Harvey Jay Cohen
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
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Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
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