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Head and neck cancers have multiple causes, but one cause in particular has become epidemic in the U.S. and in Northern Europe: HPV.
Source: bizjournals.com Health Care News Headlines - Category: Health Management Authors: Source Type: news

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This article provides a framework for decision making in the surgical and nonsurgical patient with head and neck cancer. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Speech and Language - Category: Speech-Language Pathology Authors: Tags: Review Article Source Type: research
This article provides a framework for decision making in the surgical and nonsurgical patient with head and neck cancer. PMID: 31158905 [PubMed - in process]
Source: Seminars in Speech and Language - Category: Speech-Language Pathology Authors: Tags: Semin Speech Lang Source Type: research
Authors: Boguñá N, Capdevila L, Jané-Salas E Abstract Over the last few decades, the human papillomavirus (HPV) infection has emerged as a new epidemic and become a health issue due to its involvement in several cancers affecting the cervix, the anogenital region and the oropharynx. In this review, we aim to understand and explain the distinctive features of HPV-related oropharyngeal squamous cell carcinoma based on its epidemiological data, risk factors, specific topography, HPV subtypes most frequently involved, HPV-status diagnosis, clinical behaviour, prognosis, treatment, and preventive me...
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Authors: You EL, Henry M, Zeitouni AG Abstract Oropharyngeal cancer (opc) has become the leading site for human papillomavirus (hpv)-associated cancers in humans. It is an epidemic that remains relatively unfamiliar to most physicians, potentially delaying diagnosis and treatment. Traditionally, cancers involving the head and neck have occurred in smokers and in those with a significant alcohol history. Typically, hpv-positive opc presents in a younger, healthier population with a different set of risk factors and good prognosis for survival. However, many head-and-neck cancer patients, including those with hpv-pos...
Source: Current Oncology - Category: Cancer & Oncology Tags: Curr Oncol Source Type: research
ConclusionThere is need to improve both the knowledge base and comfort level of pediatricians in counseling their patients during vaccine recommendations. Otolaryngologists have a critical role in providing education to physicians, trainees, and the general public in the effort to combat the epidemic of HPV-associated head and neck cancer.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Oral human papillomavirus (HPV) infection has rapidly become the primary causative factor driving the epidemic of HPV-related oropharyngeal squamous cell carcinoma (OPSCC). Oral infections with high-risk HPV types, most notably HPV 16, are responsible for 60% to 70% of OPSCC cases in the United States. Determining HPV infection status in patients with newly diagnosed OPSCC, most often with p16 immunostaining as a surrogate marker, is important for risk stratification and prognostication. Over the last decade, there has been increasing interest in noninvasive biomarkers for cancer, including from blood and saliva. Oral rins...
Source: JAMA Otolaryngology - Head and Neck Surgery - Category: ENT & OMF Source Type: research
Patients in both the general (noncancer) and HPV-OPC populations may enquire whether they should avoid open-mouth kissing to prevent either acquiring or transmitting oral HPV infection.
Source: ENTtoday - TRIO Best Practices - Category: ENT & OMF Authors: Tags: Head and Neck Practice Focus TRIO Best Practices clinical best practices HPV human papillomavirus Source Type: research
This article highlights the evidence-based data to support systemic treatment options for patients with head and neck squamous cell carcinoma (HNSCC). The discovery of the human papillomavirus epidemic in HNSCC and its favorable prognosis has led to a major focus of research. Patients are stratified into clinical or pathologic risk categories and enrolled in trials comparing standard treatment paradigms with deintensification, in low-risk disease, or to intensification, in intermediate-risk or high-risk disease. Immunotherapy has proven beneficial in second-line palliative therapy and is under investigation in first-line p...
Source: The Surgical Clinics of North America - Category: Surgery Authors: Tags: Oral Maxillofac Surg Clin North Am Source Type: research
This article highlights the evidence-based data to support systemic treatment options for patients with head and neck squamous cell carcinoma (HNSCC). The discovery of the human papillomavirus epidemic in HNSCC and its favorable prognosis has led to a major focus of research. Patients are stratified into clinical or pathologic risk categories and enrolled in trials comparing standard treatment paradigms with deintensification, in low-risk disease, or to intensification, in intermediate-risk or high-risk disease. Immunotherapy has proven beneficial in second-line palliative therapy and is under investigation in first-line p...
Source: Oral and Maxillofacial Surgery Clinics - Category: ENT & OMF Authors: Source Type: research
With the epidemic rise in the incidence of head and neck cancers, particularly HPV-related oropharyngeal squamous cell carcinoma [1,2], and a growing elderly population which is more susceptible to head and neck cancers [2], more patients will require treatment in an already strained healthcare environment. Since the Institute of Medicine ‘Quality Chiasm’ report in 2001 many health care systems are dedicated to a process of ongoing quality improvement and to close the performance gap in areas where current state and ideal care are wide [3–5].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research
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