The hand-held breath test that spots lung diseases in just one minute 

The device is being trialled on NHS patients with asthma and chronic obstructive pulmonary disease (COPD), a group of lung conditions including emphysema and chronic bronchitis.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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We describe the overdiagnosis and the prevalence of spirometrically defined false positive COPD, as well as their relationship with overtreatment across 23 population samples in 20 countries participating in the BOLD Study between 2003-2012. METHODS: A false positive diagnosis of COPD was considered when participants reported a doctor's diagnosis of COPD, but post-bronchodilator spirometry was unobstructed (FEV1/FVC>LLN). Additional analyses were performed using the fixed ratio criterion (FEV1/FVC
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
Conclusion: The results from this study will provide information to aid the development of prevention and intervention strategies for Aboriginal communities. PMID: 30584428 [PubMed - in process]
Source: Journal of Environmental and Public Health - Category: Environmental Health Tags: J Environ Public Health Source Type: research
Conclusions: Disease severity: 73.7%(479) had at least 1 exacerbation/year, 28.2% received antibiotic treatment, 7% presented to the emergency room, 2.7% required hospitalization. The main reason behind screening spirometry is to provide the millions of people with the right treatment and spread awareness about it.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring Airway Disease Source Type: research
CONCLUSION: The announcement of the disease did not always appear to have been of good quality. Ideally, the diagnosis of COPD should be conveyed to people after its identification in a dedicated consultation, combined with better information and a proposal for psychological support. PMID: 30415820 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Authors: Welling JBA, Slebos DJ Abstract The lung volume reduction coil treatment is a minimally invasive bronchoscopic treatment option for emphysema patients who suffer from severe hyperinflation. The treatment is aimed at a large group of patients where lung volume reduction surgery and bronchoscopic lung volume reduction using endobronchial valves are no option, or alternatively, can be offered as a bridge to lung transplantation. The nitinol coil exhibits a shape memory effect and is biologically inert. The lung volume reduction coil procedure is performed in two separate treatment sessions, targeting one lobe...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Authors: Thomson NC Abstract INTRODUCTION: Smoking-induced airway diseases such as chronic bronchitis, emphysema, and small airway dysfunction contribute to the chronic respiratory symptoms experienced by adults with asthma, including those with spirometric chronic obstructive pulmonary disease (COPD), termed asthma-COPD overlap (ACO). Drug treatment of symptomatic smokers with asthma or ACO is uncertain due to their exclusion from most clinical trials. Areas covered: This review summarizes evidence for the efficacy of small molecule drugs used in the clinic to treat current and former smokers with a diagnostic lab...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Authors: Río Ramírez MT, Juretschke Moragues MA, Fernández González R, Álvarez Rodríguez V, Aznar Andrés E, Zabaleta Camino JP, Romero Pareja R, Esteban de la Torre A Abstract The aim of this study was to analyze whether FeNO levels in acute exacerbation of COPD (AECOPD) with hospital admission have better diagnostic value than eosinophilia in blood, and to evaluate its usefulness in predicting a better clinical response. An observational prospective study of patients with AECOPD was carried out. FeNO determinations were made on arrival at the emergency room (ER), at...
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - Category: Respiratory Medicine Tags: COPD Source Type: research
Background: Chronic obstructive lung disease (COPD) is characterized by airflow obstruction not fully reversible accompanied by respiratory symptoms and exacerbations.Objectives: To evaluate the degree of control in COPD patients according to the clinical phenotype of the disease.Methods: Cross-sectional, observational, multicenter study performed simultaneously in 100 Primary Care (PC) and 37 Respiratory (RC) clinics in Spain. The classification by phenotypes of the Spanish Guide to COPD (GesEPOC) was followed. The degree of control was assessed with a score including health status (CAT questionnaire), dyspnea (mMRC) and ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems COPD Source Type: research
Conclusions: We think that reductions of HIF-1α levels in PE led to decreases in protein levels of activated LOX, LOXL1 and LOXL2, and abnormalities in elastic fiber biology. In emphysematous areas, HIF-1α activation induced by decreased COMMD1 protein can contribute to the generation of disease pathogenesis. Approaches made to increase activated LOXs and COMMD1 can be effective for the regression of PE.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Mechanisms of Lung Injury and Repair Source Type: research
Background: GINA 2014 introduced Asthma-COPD overlap syndrome (ACOS), GINA and GOLD 2015 further described it. As ACOS is still poorly recognized in China, further research is needed to improve our understanding and optimize management.Aims and Objectives: To investigate the distributions and characteristics of patients with ACOS, asthma and COPD over age 40 with airflow limitation in China.Methods: This multi-center (20 sites), cross-sectional, non-interventional study (NCT02600221) was planned to collect data from 2,000 patients over age 40 with airflow limitation (post-BD FEV1/FVC
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems Asthma Source Type: research
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