The Pathophysiology and Treatment of Hypertension in Patients With Cushing's Syndrome

This article discusses the mechanisms involved in the pathogenesis of CS and the pros and the cons of the various antihypertensive agents that are presently available to treat these patients.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research

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(Oxford University Press USA) A new study soon to appear in the Faculty of Public Health's Journal of Public Health, published by Oxford University Press, suggests that air pollution and living in apartment buildings may be associated with an increased risk for dangerous conditions like heart disease, stroke, and type 2 diabetes. This paper is embargoed until midnight EST on June 25.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
ConclusionsHaemodynamic, biochemical alteration and histopathological results suggest a cardioprotective protective effect of oral administration of AZE in isoproterenol induced cardiotoxicity.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 22 June 2019Source: Practical Radiation OncologyAuthor(s): Bindu V. Manyam, Chirag Shah, Neil M. Woody, Chandana A. Reddy, Michael A. Weller, Aditya Juloori, Mihir Naik, Stephanie Valente, Stephen Grobmyer, Paul Durand, Risal Djohan, Rahul D. TendulkarAbstractPurposeThe toxicity profile of breast reconstruction with post-mastectomy radiation therapy (PMRT) varies by technique and timing, and long-term data are limited. We compared rates of complications requiring re-operation (CRR) and reconstruction failure (RF) between immediate autologous reconstruction (I-AR), immediate tissue expande...
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
The Food and Drug Administration (FDA) on Fridayapproved Vyleesi (bremelanotide) to treat premenopausal women for acquired, generalized hypoactive sexual desire disorder (HSDD). HSDD (classified as female sexual interest/arousal disorder inDSM-5) is characterized by low sexual desire that causes distress and cannot be explained by a comorbid physical or psychiatric illness, the side effects of substance use or medications, or severe relationship problems. Acquired HSDD means a woman has previously experienced sexual desire (it has not been a lifelong problem).“There are women who, for no known reason, have reduced se...
Source: Psychiatr News - Category: Psychiatry Tags: blood pressure female sexual interest/arousal disorder hypoactive sexual desire disorder naltrexone premenopausal women sexual dysfunction Vyleesi Source Type: research
BOSTON (CBS) – Don’t let your vacation time go to waste. A new study out of Syracuse University provides “medical proof” that vacation is good for your heart. According to experts, vacation time is available to nearly 80-percent of full-time employees but fewer than half take all the time allotted. So researchers studied 63 workers eligible for paid vacation and found that people who vacation more frequently in the past 12 months have a lower risk of metabolic syndrome, a collection of risk factors for heart disease like high blood pressure, high blood sugar and high cholesterol. In fact, the risk f...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Vacations Source Type: news
The authors of this open access paper review the aging of the kidney and consider the prospects for using factors from young blood as a means of rejuvenation. This is a fairly narrow view, as there are many other approaches that should produce rejuvenation of the aged kidney, ranging from those close to realization, such as senolytic therapies to clear senescent cells, or various approaches to stem cell therapy, to those yet to be achieved, meaning much of the rest of the SENS agenda of rejuvenation biotechnologies to repair the damage that causes aging. Nonetheless, after so many years of trying to persuade the research c...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
HIGH blood pressure is often dubbed the “silent killer”. More than one in four people have it in the UK yet many will not realise it. There are various steps people can take to control a blood pressure spike. Research suggests one popular ingredient might do the trick.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The practice of genomic medicine stands to revolutionize our approach to medical care, and to realize this goal will require discovery of the relationship between rare variation at each of the ~  20,000 protein...
Source: Orphanet Journal of Rare Diseases - Category: Internal Medicine Authors: Tags: Review Source Type: research
Estimation of incidence in rare diseases is often challenging due to unspecific and incomplete coding and recording systems. Patient- and health care provider-driven data collections are held with different or...
Source: Orphanet Journal of Rare Diseases - Category: Internal Medicine Authors: Tags: Research Source Type: research
Conclusion In patients with advanced non-squamous NSCLC, the feasible dose of apatinib given with standard-dose pemetrexed and carboplatin was 500  mg/day schedule 2/1. The schedule was generally well tolerated and demonstrated promising clinical benefit in NSCLC.
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research
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