MicroRNA Profiling in HIV-Infected South African Women with Gestational Diabetes Mellitus

ConclusionOur results demonstrate that HIV infection modifies the expression of miR-20a-5p and miR-222-3p in women with GDM. Importantly, this study highlights the complexities of miRNA profiling and the need for GDM biomarker discovery in both HIV-infected and uninfected individuals, particularly in South Africa, where approximately 30% of pregnancies are complicated by HIV. Further studies to elucidate the mechanisms that underlie these miRNA differences are needed.
Source: Molecular Diagnosis and Therapy - Category: Molecular Biology Source Type: research