Statin use associated with reduced risk of dementia after concussion in older adults

(JAMA Network) Concussion is a common brain injury. This observational study of nearly 29,000 adults (66 and older) diagnosed with concussion examined whether statin use was associated with risk of long-term dementia after a concussion.
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Conclusion: Textures of the hippocampus, precuneus and posterior cingulate cortex predicted conversion from MCI to Alzheimer disease at an earlier time point and with higher accuracy than hippocampal volume. PMID: 31228173 [PubMed - as supplied by publisher]
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If we were proactive, we’ve already discussed the choices for living arrangements our loved ones would have made for themselves under differing circumstances, however, many people haven’t done this. Either way, we move forward. We need to consider whether aging-in-place is a realistic choice, with in-home care agencies providing care, or if our loved one will be safer living in a nursing home. Understand that even if you had the conversation earlier, you may have to go against their wishes. View the slideshow on HealthCentral to learn more about what you should consider before placing someone in ...
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Conclusions: In the acute phase of mild TBI a majority of patients has impaired olfactory function. Further patients with olfactory dysfunction are more likely to exhibit post-concussion and anxious symptoms at follow-up. Olfactory testing in the acute phase may therefore serve as a screening tool for long-term outcome. PMID: 31223039 [PubMed - as supplied by publisher]
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Concussion in older adults is tied to a dramatically increased risk for dementia, but new research suggests statins may mitigate this risk.Medscape Medical News
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MONDAY, May 20, 2019 -- Older adults have an increased risk for dementia after concussion, which is modestly reduced among patients using a statin, according to a study published online May 20 in JAMA Neurology. Donald A. Redelmeier, M.D., from the...
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Researchers at the University of Toronto found elderly people who received the drug after a hit to the head were 13 percent less likely to develop dementia then those who didn't.
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Interview with Donald A. Redelmeier, MD, FRCPC, MSHSR, FACP, author of Association Between Statin Use and Risk of Dementia After a Concussion
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This large extended population-based double cohort study tests whether statin use is associated with an increased or decreased risk of subsequent dementia after a concussion among older adults.
Source: JAMA Neurology - Category: Neurology Source Type: research
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