Detection of serum protein and circulating mRNA of cMET, HGF EGF and EGFR levels in lung cancer patients to guide individualized therapy.

CONCLUSION: To our knowledge this is the first study comparing the levels of protein and mRNA in the serum material of HGF, c-MET, EGF and EGFR parameters in lung cancer patients' blood samples. Further prospective studies with more participants for better understanding of mechanism and effect for HGF and c-MET inhibitors in lung cancer will help us to identify of these biomarkers role for guiding us to sellect individualized itargeted therapies. PMID: 31104010 [PubMed - as supplied by publisher]
Source: Cancer Biomarkers - Category: Cancer & Oncology Tags: Cancer Biomark Source Type: research

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Authors: Latha S, Selvamani P, Prabha T Abstract Natural products have a unique place in the healthcare industry. The genus Commiphora emerged as a potential medicinal with huge benefits as evidenced through its use in various traditional and modern systems of medicine. Therefore, we aimed to prepare a concise review on the pharmacological activities and the indigenous uses of various plant species belonging to the genus Commiphora along with the structural information of various active botanical ingredients present in these plants based on the published literatures and scientific reports. To collect the various pu...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - Category: Cardiology Tags: Cardiovasc Hematol Agents Med Chem Source Type: research
Publication date: Available online 3 July 2020Source: European UrologyAuthor(s): Giuseppe Di Lorenzo, Riccardo Autorino
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 3 July 2020Source: European UrologyAuthor(s): Christian D. Fankhauser, Kathryn L. Penney, Amparo G. Gonzalez-Feliciano, Noel W. Clarke, Thomas Hermanns, Konrad H. Stopsack, Michelangelo Fiorentino, Massimo Loda, Brandon Mahal, Travis A. Gerke, Mark A. Preston, Lorelei A. Mucci
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 3 July 2020Source: European UrologyAuthor(s): David E. Neal, Chris Metcalfe, Jenny L. Donovan, J. Athene Lane, Michael Davis, Grace J. Young, Susan J. Dutton, Eleanor I. Walsh, Richard M. Martin, Tim. J. Peters, Emma L. Turner, Malcolm Mason, Richard Bryant, Prasad Bollina, James Catto, Alan Doherty, David Gillatt, Vincent Gnanapragasam, Peter Holding, Owen Hughes
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 2 July 2020Source: European UrologyAuthor(s): Carlo A. Bravi, Nicola Fossati, Giorgio Gandaglia, Nazareno Suardi, Elio Mazzone, Daniele Robesti, Daniar Osmonov, Klaus-Peter Juenemann, Luca Boeri, R. Jeffrey Karnes, Alexander Kretschmer, Alexander Buchner, Christian Stief, Andreas Hiester, Alessandro Nini, Peter Albers, Gaëtan Devos, Steven Joniau, Hendrik Van Poppel, Shahrokh F. Shariat
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 2 July 2020Source: European UrologyAuthor(s): Alexandre R. Zlotta, Sigrid V. Carlsson, Antonio Finelli, Neil E. Fleshner
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 2 July 2020Source: European UrologyAuthor(s): Francesco Massari, Veronica Mollica
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 2 July 2020Source: European UrologyAuthor(s): Philip Cornford, Jeremy Grummet, Stefano Fanti, on behalf of the EAU-EANM-ESTRO-ESUR-SIOG Prostate Cancer Guidelines Panel
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 2 July 2020Source: European UrologyAuthor(s): Carlo A. Bravi, Nicola Fossati, Giorgio Gandaglia, Nazareno Suardi, Elio Mazzone, Daniele Robesti, Daniar Osmonov, Klaus-Peter Juenemann, Luca Boeri, R. Jeffrey Karnes, Alexander Kretschmer, Alexander Buchner, Christian Stief, Andreas Hiester, Alessandro Nini, Peter Albers, Gaëtan Devos, Steven Joniau, Hendrik Van Poppel, Shahrokh F. Shariat
Source: European Urology - Category: Urology & Nephrology Source Type: research
Conclusions Knowing that the incidence of lung cancer increased globally in both male and female, the relatively lower male to female ratio when compared with other studies, may reflect at least an increasing in the lung cancer rates among female. Smoking still remains the major risk factor in pathogenesis of primary lung cancer. COPD could be considered an important respiratory disorder that tied to bronchogenic carcinoma risk. Interestingly, the incidence of adenocarcinoma surpassed that of squamous cell carcinoma. Unfortunately, presentation of the patient at later stages of illness was common.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - Category: Respiratory Medicine Source Type: research
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