Statins lower the elevated risk of dementia after a concussion
Researchers at the University of Toronto found elderly people who received the drug after a hit to the head were 13 percent less likely to develop dementia then those who didn't.
Publication date: Available online 26 February 2020Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Ben Ponvilawan, Nipith Charoenngam, Thanitsara Rittiphairoj, Patompong Ungprasert
CONCLUSION: All these results indicate that SQC is an effective preventive and protective drug on skeletal muscle of diabetic macrovasculopathy, and could alleviate skeletal muscle tissue damage through affecting biological functions related to cell death and cell adhesion. PMID: 32096754 [PubMed - as supplied by publisher]
CONCLUSIONS: In patients with anterior cerebral artery-occluded AIS, the TC level is a promising prognosis marker for the IV thrombolysis outcome. PMID: 32096200 [PubMed - in process]
There are inconsistent results on the association between statin use and the risk of dementia. Power et al. conducted a systematic review and concluded that randomized controlled trials (RCTs) and well-conducted observational studies did not support a ...
There are inconsistent results on the association between statin use and the risk of dementia. Power et al. conducted a systematic review and concluded that randomized controlled trials (RCTs) and well-conducted observational studies did not support a causal preventative effect of late-life statin use on cognitive decline or dementia . As concussion is a risk factor of dementia, Redelmeier et al. recently conducted a prospective study to evaluate the association between statin use and the risk of dementia after a concussion in older adults .
Concussion in older adults is tied to a dramatically increased risk for dementia, but new research suggests statins may mitigate this risk.Medscape Medical News
MONDAY, May 20, 2019 -- Older adults have an increased risk for dementia after concussion, which is modestly reduced among patients using a statin, according to a study published online May 20 in JAMA Neurology. Donald A. Redelmeier, M.D., from the...
Interview with Donald A. Redelmeier, MD, FRCPC, MSHSR, FACP, author of Association Between Statin Use and Risk of Dementia After a Concussion
(JAMA Network) Concussion is a common brain injury. This observational study of nearly 29,000 adults (66 and older) diagnosed with concussion examined whether statin use was associated with risk of long-term dementia after a concussion.
This large extended population-based double cohort study tests whether statin use is associated with an increased or decreased risk of subsequent dementia after a concussion among older adults.