JAMA Neurology : Association Between Statin Use and Risk of Dementia After a Concussion

Interview with Donald A. Redelmeier, MD, FRCPC, MSHSR, FACP, author of Association Between Statin Use and Risk of Dementia After a Concussion
Source: JAMA Specialty Journals Author Interviews - Category: General Medicine Source Type: podcasts

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Women who naturally exhibit lower levels of an enzyme blocked by statins have an estimated 40 per cent lower risk of ovarian cancer, a study by Bristol University found.
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Publication date: Available online 17 February 2020Source: Annals of Emergency MedicineAuthor(s): Rebekah Mannix, Jeffrey J. Bazarian
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There are inconsistent results on the association between statin use and the risk of dementia. Power et al. conducted a systematic review and concluded that randomized controlled trials (RCTs) and well-conducted observational studies did not support a ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
There are inconsistent results on the association between statin use and the risk of dementia. Power et al. conducted a systematic review and concluded that randomized controlled trials (RCTs) and well-conducted observational studies did not support a causal preventative effect of late-life statin use on cognitive decline or dementia [1]. As concussion is a risk factor of dementia, Redelmeier et al. recently conducted a prospective study to evaluate the association between statin use and the risk of dementia after a concussion in older adults [2].
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
Concussion in older adults is tied to a dramatically increased risk for dementia, but new research suggests statins may mitigate this risk.Medscape Medical News
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MONDAY, May 20, 2019 -- Older adults have an increased risk for dementia after concussion, which is modestly reduced among patients using a statin, according to a study published online May 20 in JAMA Neurology. Donald A. Redelmeier, M.D., from the...
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Researchers at the University of Toronto found elderly people who received the drug after a hit to the head were 13 percent less likely to develop dementia then those who didn't.
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(JAMA Network) Concussion is a common brain injury. This observational study of nearly 29,000 adults (66 and older) diagnosed with concussion examined whether statin use was associated with risk of long-term dementia after a concussion.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
This large extended population-based double cohort study tests whether statin use is associated with an increased or decreased risk of subsequent dementia after a concussion among older adults.
Source: JAMA Neurology - Category: Neurology Source Type: research
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