Human Hereditary Deafness is Complex Yet Easy to Grasp

Beyond the Lab, Understanding Communication Disorders: Speaker Series Learn how deafness can be inherited (passed down through generations). Genetic research can improve our understanding of which gene variants are associated with human hereditary deafness. By identifying these gene variants, scientists may be able to diagnose certain forms of hereditary hearing loss earlier and more accurately. The program is part of the Beyond the Lab speaker series offered by the National Institute on Deafness and Other Communication Disorders (NIDCD). Designed for administrative and support staff as well as scientists, the speaker series gives the NIH community an opportunity to learn about NIDCD's research and research advances.For more information go to date: 5/28/2019 12:00:00 PM
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video

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Publication date: Available online 16 August 2019Source: Speech CommunicationAuthor(s): Arthur Lewis Thompson, Youngah DoAbstractSome languages have more forms of conventional spoken iconicity than others. Japanese, for example, has more ideophones than English. So how do speakers of a language with limited semantic categories of ideophones depict percepts? One possibility is demonstrations: unconventional, yet depictive, discourse. Demonstrations follow quotatives (e.g., I was like ___) and perform referents as opposed to describing them. In English, a language with arguably restricted sets of ideophones, speakers may ena...
Source: Speech Communication - Category: Speech-Language Pathology Source Type: research
Conclusion: Children received an immediate benefit by a burst of WRS growth from CI-2 earlier than CI-1, even within 3 months, suggesting that CI-1 gets the auditory cortex ready to foster speech processing from CI-2. The CI-2 performance depends on age at CI-2 implantation and on CI-1 performance. Our current findings will be relevant for clinicians who are counselling parents on CI-2 surgery.
Source: Otology and Neurotology - Category: ENT & OMF Tags: COCHLEAR IMPLANTS Source Type: research
Conclusion: A significant performance gap in speech recognition is observed between percutaneous and transcutaneous bone-conduction stimulation in individuals with single-sided deafness at the same signal to noise ratios. Compared with percutaneous bone-conduction stimulation, transcutaneous stimulation demonstrated reduced effective gain, decreased phoneme recognition, word recognition, and performance in noise, with the most significant impact observed for soft speech inputs.
Source: Otology and Neurotology - Category: ENT & OMF Tags: PROSTHETIC DEVICES Source Type: research
ConclusionSymptoms of eighth nerve dysfunction are present in over half of patients with GCA. Recovery with steroids was predicted by concurrence with headache in terms of both timing and location. It appears that eighth nerve involvement, especially acute hearing loss, is a not infrequent feature of GCA and often responds well to steroid therapy. Clinicians should enquire about these symptoms when evaluating a patient for possible GCA.Key Points• Deafness is a frequent presenting feature of giant cell arteritis.• Vertigo, tinnitus and loss of balance are also often reported by GCA sufferers.• Steroid therap...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Better care for Parkinson ’s, MS and motor neurone disease Related items fromOnMedica 'Revived' dead pig brains offer new research hopes NICE issues guidelines on neurological conditions GPs have duty to protect abused vulnerable adults NICE sets care standards for spasticity GPs must greatly improve deaf awareness
Source: OnMedica Latest News - Category: UK Health Source Type: news
ConclusionOverall, segmental and suprasegmental perception as well as sentence-level processing is impaired in Mandarin-speaking children with CIs compared with age-matched children with NH. In children with CIs recognition of segmental and suprasegmental phonemes at the lower level predicts sentence repetition accuracy at the higher level. More importantly, implantation age plays an important role in the development of phonological skills and higher-order language skills, suggesting that age-appropriate aural rehabilitation and speech intervention programs need to be developed in order to better help CI users who receive ...
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Conclusion The formant frequency upshifts, fundamental frequency upshifts, and metallic sound quality experienced by the listeners can be linked to the relatively basal locations of the electrode contacts and short duration experience with their devices. The perceptual consequence was not the voice quality of Mickey Mouse™ but rather that of Munchkins in The Wizard of Oz for whom both formant frequencies and voice pitch were upshifted. Supplemental Material PMID: 31415186 [PubMed - as supplied by publisher]
Source: Journal of speech, language, and hearing research : JSLHR - Category: Speech-Language Pathology Authors: Tags: J Speech Lang Hear Res Source Type: research
Genetics in Medicine, Published online: 15 August 2019; doi:10.1038/s41436-019-0638-3We must now put in place an updated, comprehensive newborn screening program for deaf and hard-of-hearing infants
Source: Genetics in Medicine - Category: Genetics & Stem Cells Authors: Source Type: research
Publication date: Available online 13 August 2019Source: Journal of Genetics and GenomicsAuthor(s): Jun Yao, Huasha Zeng, Min Zhang, Qinjun Wei, Ying Wang, Haiyuan Yang, Yajie Lu, Rongfeng Li, Qiang Xiong, Lining Zhang, Zhibin Chen, Guangqian Xing, Xin Cao, Yifan DaiAbstractOxysterol binding protein like 2 (OSBPL2), an important regulator in cellular lipid metabolism and transport, was identified as a novel deafness-causative gene in our previous work. To resemble the phenotypic features of OSBPL2 mutation in animal models and elucidate the potential genotype-phenotype associations, the OSBPL2-disrupted Bama miniature (BM)...
Source: Journal of Genetics and Genomics - Category: Genetics & Stem Cells Source Type: research
PMID: 31408183 [PubMed - as supplied by publisher]
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
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