Immune checkpoint inhibitor therapy and myocarditis: a systematic review of reported cases

ConclusionMost cases and fatalities of myocarditis occurred shortly after initiation of immune checkpoint inhibitor therapy. Arrhythmias, particularly complete heart block, appear to be related to the occurrence of more severe and fatal cases. The use of serial electrocardiograms or biomarkers of myocardial injury may be crucial in detecting early stages of the disease process. Further research establishing more specific guidelines is necessary in dealing with this potentially fatal side effect.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research