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Critically ill flu patients saved with artificial lung technology treatment

In recent weeks, the intensive critical care units at University Health Network's Toronto General Hospital have used Extra Corporeal Lung Support to support five influenza patients in their recovery from severe respiratory problems.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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CONCLUSIONS Despite great progress in the management of ARDS, based mostly on advanced mechanical ventilation, early antiviral treatment of pneumonia caused by influenza A (H1N1) and annual vaccinations seem essential in prevention and management of influenza A (H1N1) infection among kidney transplant recipients. PMID: 29599422 [PubMed - in process]
Source: Annals of Transplantation - Category: Transplant Surgery Authors: Tags: Ann Transplant Source Type: research
This report shows that unexpected native lung recovery is possible even after prolonged loss of lung function an d that a previous healthy lung can recover from apparent irreversible lung injury.
Source: Journal of Artificial Organs - Category: Transplant Surgery Source Type: research
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Source: Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Conclusion: Donor transmission and early acquisition of CARV (particularly Flu A) occur frequently after LTX, with delayed viral clearance, emphasising the importance of respiratory virome surveillance.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Transplantation Source Type: research
We examined associations between mortality and accelerometer-measured PA using age-relevant intensity cutpoints in older women of various ethnicities. The results support the hypothesis that higher levels of accelerometer-measured PA, even when below the moderate-intensity threshold recommended in current guidelines, are associated with lower all-cause and CVD mortality in women aged 63 to 99. Our findings expand on previous studies showing that higher self-reported PA reduces mortality in adults aged 60 and older, specifically in older women, and at less than recommended amounts. Moreover, our findings challenge th...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
AbstractPurposeDespite, vaccination is a highly effective and widely recommended for prevention of certain infections, vaccination coverage is very low. The purposes of this study were to evaluate the attitudes of medical oncologists towards vaccination and to identify predictors of intention to recommend vaccination in patients with cancer.MethodsA structured questionnaire is formed to evaluate the daily practice of vaccination. Turkish medical oncologists were invited to this study via email, SMS, or phone call. Questionnaire was filled out and the data were stored in an online survey platform.ResultsTwo hundred seventy-...
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
Discussion α-1-Antitrypsin Deficiency (A1AT) is a common single-gene mutation disease that is homozygous recessive. The normal allele is called M and the most common abnormal allele is Z. There are other alleles though. The gene codes for one of the primary protease inhibitors in the serum, thus those who are homozygous for the Z gene are sometimes referred to as “PIZZ” or “PIZ.” α-1-Antitrypsin is found in all body tissues but is especially important in the serum and lung. As noted it is one of the primary neutrophil protease inhibitors in the serum, and acts to neutralize these enzymes...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
AbstractExtracorporeal membrane oxygenation (ECMO) or extracorporeal life support (ECLS) is a form of heart lung bypass that is used to support neonates, pediatrics, and adult patients with cardiorespiratory failure for days or weeks till organ recovery or transplantation. Venoarterial (VA) and venovenous (VV) ECLS are the most common modes of support. ECLS circuit components and monitoring have been evolving over the last 40  years. The technology is safer, simpler, and more durable with fewer complications. The use of neonatal respiratory ECLS use has been declining over the last two decades, while adult respiratory...
Source: Current Anesthesiology Reports - Category: Anesthesiology Source Type: research
The objective of this study was to collect and analyze data to demonstrate the burden of influenza infection in pediatric lung transplant patients at Texas Children ’s Hospital. This descriptive study will serve as background information for further studies regarding current influenza vaccine prevention and antiviral treatment protocol efficacy in pediatric lung transplant populations.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Pneumonia is a major cause of morbidity in pts undergoing HSCT and AL therapy. Early FOB with culture, cytopath and viral ELISA testing improves survival. Early FOB at our center historically identified causative microorganism(s) in 37% of pts (68/183). We conducted an IRB approved prospective early FOB trial in 49 pts undergoing HSCT or AL therapy with respiratory symptoms and new radiographic lung infiltrates to determine the impact of the rapid PCR panel combined with culture testing. The PCR panel included Mycoplasma, Chlamydia, HSV, VZV, HHV7, RSV, hMPV, Rhino/Coronavirus, Adenovirus, Influenza A/B, Parainfluenza Type...
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research
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