Stability test of novel combined formulated dry powder inhalation system containing antibiotic: Physical characterization and in vitro-in silico lung deposition results.

CONCLUSION: It can be established that after the storage a novel combined formulated DPI contained amorphous drug to have around 2.5 μm mass median aerodynamic diameter and nearly 50% fine particle fraction predicted high lung deposition in silico also. PMID: 31096805 [PubMed - as supplied by publisher]
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research