Evaluation of Prehospital Management in a Canadian Emergency Department Anaphylaxis Cohort

ConclusionsPrompt epinephrine treatment is crucial. Use of antihistamines in conjunction with epinephrine may reduce the risk of uncontrolled reactions (administration of 2 or more doses of epinephrine in the ED), although our findings do not support the use of corticosteroids.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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CONCLUSIONS: The rate of anaphylaxis in patients with ColdU in a tropical country was lower than those reported by other studies conducted intemperate climates. On the other hand, the number of female patients, mean age at symptom onset, atopy rate, rate of concomitant chronic spontaneous urticaria and mean CTT were higher. PMID: 31172722 [PubMed]
Source: Allergy, Asthma and Immunology Research - Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
ConclusionsPrompt epinephrine treatment is crucial. Use of antihistamines in conjunction with epinephrine may reduce the risk of uncontrolled reactions (administration of 2 or more doses of epinephrine in the ED), while our findings do not support the use of steroids.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Anaphylaxis in Elderly Patients—Data From the European Anaphylaxis Registry Stefanie Aurich1†, Sabine Dölle-Bierke2†, Wojciech Francuzik2, Maria Beatrice Bilo3, George Christoff4,5, Montserrat Fernandez-Rivas6, Thomas Hawranek7, Claudia Pföhler8, Iwona Poziomkowska-Gȩsicka9, Jean-Marie Renaudin10, Eva Oppel11, Kathrin Scherer12, Regina Treudler1‡ and Margitta Worm2*‡on behalf of The Network for Online Registration of Anaphylaxis(NORA)§ 1Department of Dermatology, Venereology and Allergology, LICA-Comprehensive Allergy Center, University Hospital, Leipzig, Germany 2Di...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Anaphylaxis affects 1.6%-5.1% of adults. Treatment with epinephrine is generally effective, and supplementary medications can be used for prevention/treatment of anaphylactoid symptoms. Common adjuncts include corticosteroids and antihistamines. Radiocontrast is necessary for evaluation of certain conditions and cannot always be avoided even with history of reaction. While underlying mechanisms of contrast reactions are not well-understood, premedication with corticosteroids/antihistamines can often be used for prevention of reactions.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: M055 Source Type: research
ConclusionIndividual healthcare plan is mainly implemented for FA. Anaphylaxis remains rare in the school setting, and FA is often a suspected cause of reaction. Staff training should be improved. Application of the recommendations regarding the content and accessibility of EK and a widespread emergency action plan is needed.
Source: Pediatric Allergy and Immunology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionIHP is mainly implemented for FA. Anaphylaxis remains rare in the school setting and FA is often a suspected cause of reaction. Staff training should be improved. Application of the recommendations regarding the content and accessibility of EK and a widespread emergency action plan are needed.This article is protected by copyright. All rights reserved.
Source: Pediatric Allergy and Immunology - Category: Allergy & Immunology Authors: Tags: Original Source Type: research
Publication date: Available online 3 July 2017 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): G. Mortuaire, J. Michel, J.F. Papon, O. Malard, D. Ebbo, L. Crampette, R. Jankowski, A. Coste, E. Serrano Allergic rhinitis is a common condition, with significant impact on quality of life depending on severity and quality of control. Allergen-specific immunotherapy (allergen-SIT) is the only known treatment able to alter the natural course of allergic rhinitis. Although well known to allergologists, it has yet to be fully adopted by the ENT community. This review, based on the most recent meta-...
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
Opinion statementIdiopathic anaphylaxis is a rare life-threatening disorder with symptoms similar to other forms of anaphylaxis. There is lack of a robust evidence base underpinning the treatment of anaphylaxis and even less so for idiopathic anaphylaxis. Much of the evidence therefore comes from relatively small case series and expert opinion. Idiopathic anaphylaxis is a diagnosis of exclusion, requiring a thorough history and careful diagnostic work-up investigating possible triggers and underlying predisposing factors. Key diagnostic tests include skin-prick testing, tests for specific-IgE, component-resolved diagnostic...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
Authors: Navinés-Ferrer A, Serrano-Candelas E, Molina-Molina GJ, Martín M Abstract IgE is an immunoglobulin that plays a central role in acute allergic reactions and chronic inflammatory allergic diseases. The development of a drug able to neutralize this antibody represents a breakthrough in the treatment of inflammatory pathologies with a probable allergic basis. This review focuses on IgE-related chronic diseases, such as allergic asthma and chronic urticaria (CU), and on the role of the anti-IgE monoclonal antibody, omalizumab, in their treatment. We also assess the off-label use of omalizumab for...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
DISCUSSION SESSION 1: Food allergy (PD01 –PD05)PD01 Allergen-specific humoral and cellular responses in children who fail egg oral immunotherapy due to allergic reactionsMarta Vazquez-Ortiz, Mariona Pascal, Ana Maria Plaza, Manel JuanPD02 FoxP3 epigenetic features in children with cow milk allergyLorella Paparo, Rita Nocerino, Rosita Aitoro, Ilaria Langella, Antonio Amoroso, Alessia Amoroso, Carmen Di Scala, Roberto Berni CananiPD04 Combined milk and egg allergy in early childhood: let them eat cake?Santanu Maity, Giuseppina Rotiroti, Minal GandhiPD05 Introduction of complementary foods in relation to allergy and gut...
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
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