Obesity and neurological disorders: Dietary perspective of a global menace
Emerging Knowledge for Clinical Practice Podium Presentations focusing on the Research Agenda Priority of Pediatric Research: Professional Role&Health Promotion and Disease Prevention, Presented at NAPNAP's 40th National Conference on Pediatric Health Care, March 8, 2019, New Orleans, LA.
This article will present an overview of metabolic syndrome, pediatric metabolic syndrome guidelines, pathophysiology, associated risk factors, and clinical practice implications.
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
ConclusionsTaken together, our data provided a novel insight into the role of XXT in losing weight from energy metabolism regulation, which unraveled the molecular mechanism of XXT on the alleviation of dyslipidemia and fat heterotopic accumulation. The study provided useful information for XXT in clinical application to treat obesity.Graphical abstract
(Reuters Health) - Long-term use of prescription opioids for chronic pain is more common among people who are overweight or obese, a new study finds.
In 2014, the government food assistance program expanded access to healthier foods, and it seems to have paid off. Obesity among preschoolers fell from 16% to 14%, the CDC reports.
“In bariatric laparoscopic surgery, two specific conditions worsen obesity-related respiratory disorders and increase the anesthetic risk: [pneumoperitoneum and Trendelenburg position].”
“[R]ecruitment maneuvers may still be useful in overweight (and obese) patients to reduce atelectasis…[but not] in elderly patients…[where] one should consider increasing lung volume, such as through the use of positive end-expiratory pressure…”
Editor ’s PerspectiveWhat We Already Know about This TopicDuring anesthesia oxygenation is impaired, especially in the elderly or obese, but the mechanisms are uncertain.What This Article Tells Us That Is NewPooled data were examined from 80 patients studied with multiple inert gas elimination technique and computed tomography. Oxygenation was impaired by anesthesia, more so with greater age or body mass index. The key contributors were low ventilation/perfusion ratio (likely airway closure) in the elderly and shunt (atelectasis) in the obese.Background Anesthesia is increasingly common in elderly and overweight pati...
Conclusions In obese patients, complete airway closure is frequent during anesthesia and is worsened by Trendelenburg pneumoperitoneum, which increases airway opening pressure and alveolar pressure: besides preventing alveolar derecruitment, this yields misinterpretation of respiratory mechanics and generates a pressure threshold to inflate the lung that can reach high values, spreading concerns on the safety of pressure-controlled modes in this setting.