Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials.

Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Am J Chin Med. 2019 May 16;:1-17 Authors: Zhang LS, Zhang JH, Feng R, Jin XY, Yang FW, Ji ZC, Zhao MY, Zhang MY, Zhang BL, Li XM Abstract To systematically evaluate the efficacy and safety of berberine for the treatment of hyperlipidemia, six electronic literature databases including SinoMed, CNKI, WanFang Data, PubMed, Embase and The Cochrane Library were searched to collect clinical randomized controlled trials (RCTs) of berberine alone or combined with statins for the treatment of hyperlipidemia from the inception to 8 March 2018. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included RCTs. Then, meta-analysis was performed by using RevMan 5.3 software. A total of 11 RCTs involving 1386 patients were finally included. The results of meta-analysis showed that compared with the placebo group, berberine could significantly reduce the total cholesterol and low-density lipoprotein levels and elevate the high density lipoprotein level ( P
Source: The American Journal of Chinese Medicine - Category: Complementary Medicine Authors: Tags: Am J Chin Med Source Type: research

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ConclusionsPatients presenting with abdominal pain, diarrhoea, or bloody stool need to be evaluated for the possibility of this condition and treated accordingly. Timely diagnosis is necessary to improve patient outcomes. This review aims to increase awareness among clinicians regarding the presentation of pharmacologically induced colonic ischaemia.
Source: Alimentary Pharmacology and Therapeutics - Category: Drugs & Pharmacology Authors: Tags: REVIEW ARTICLE Source Type: research
BY SHANNON BROWNLEE On Wednesday, October 25, 2017 I was at the inaugural Society for Participatory Medicine conference. It was a fantastic day and the ending keynote was the superb Shannon Brownlee. It was great to catch up with her and I’m grateful that she agreed to let THCB publish her speech. Settle back with a cup of coffee (or as it’s Thanksgiving, perhaps something stronger), and enjoy–Matthew Holt George Burns once said, the secret to a good sermon is to have a good beginning and a good ending—and to have the two as close together as possible. I think the same is true of final keynotes aft...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: OP-ED Patients Physicians Lown Institute Overtreatment Right Choice Alliance Shannon Brownlee Society for Participatory Medicine Source Type: blogs
CONCLUSION: This paper confirms earlier work that medication-related harms are common, occur both in hospitals and in the community, and are a substantial burden for patients and our healthcare system. Work is underway at local and national levels to decrease this harm, with a focus on the high-risk medicines most commonly implicated. PMID: 28796769 [PubMed - in process]
Source: New Zealand Medical Journal - Category: General Medicine Tags: N Z Med J Source Type: research
Abstract Several studies have reported constipation, abdominal pain, or diarrhea as common adverse events for statins. Statins are among the most commonly prescribed medications, and the impact on the prevalence of these conditions was rarely studied as main outcomes. The aim of this study is to determine if statin therapy is associated with constipation, abdominal pain, diarrhea, or colitis. This was a retrospective cohort study using a regional military health care data from October 1, 2003, to March 1, 2012. A propensity score-matched cohort of statin users and nonusers was created based on 82 variables. The pr...
Source: The Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Authors: Tags: J Clin Pharmacol Source Type: research
The Wheat Belly Total Health approach begins with wheat and grain elimination . . . but does not end there. Followers of this program understand that eliminating wheat and grains that started so many health and weight problems removes the initial cause. But many health issues can persist in their wake, some caused by wheat/grains, others just due to common nutritional deficiencies with broad health implications. For this reason, there are additional strategies to follow if you hope to regain and maintain ideal health. These strategies include correction of magnesium and iodine deficiencies, restoration of vitamin D, achiev...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Success Stories autoimmune edema gastrointestinal gluten grains Inflammation joint pain swelling Weight Loss Source Type: blogs
This in the UK. What is euphemistically referred to as an " IT system error " is, in reality, the mass delivery of a grossly defective medical device adversely affecting hundreds of thousands of patients.   I'm surprised not to see that other kindly euphemism, " glitch " ( http://hcrenewal.blogspot.com/search/label/glitch ): http://www.pulsetoday.co.uk/your-practice/practice-topics/it/gps-told-to-review-patients-at-risk-as-it-error-miscalculates-cv-score-in-thousands/20031807.article 11 May 2016   By Alex Matthews-King Hundreds of thousands of patients have potentially been given an ...
Source: Health Care Renewal - Category: Health Management Tags: Alex Matthews-King Clinical Safety Incident Dr Grant Ingrams glitch Harry Potter Patient care has not been compromised Source Type: blogs
This in the UK.What is euphemistically referred to as an "IT system error" is, in reality, the mass delivery of a grossly defective medical device adversely affecting hundreds of thousands of patients.  I'm surprised not to see that other kindly euphemism, "glitch" (http://hcrenewal.blogspot.com/search/label/glitch):http://www.pulsetoday.co.uk/your-practice/practice-topics/it/gps-told-to-review-patients-at-risk-as-it-error-miscalculates-cv-score-in-thousands/20031807.article11 May 2016  By Alex Matthews-KingHundreds of thousands of patients have potentially been given an incorrect cardiovascul...
Source: Health Care Renewal - Category: Health Management Tags: Alex Matthews-King Clinical Safety Incident Dr Grant Ingrams glitch Harry Potter Patient care has not been compromised Source Type: blogs
Halil M Abstract BACKGROUND: The aim of this study was to demonstrate the prevalence and possible predictors of potentially inappropriate medications (PIMs) and potentially prescription omissions (PPOs) according to the Screening Tool of Older Person's Prescriptions (STOPP) and Screening Tool to Alert doctors to Right Treatment (START) criteria in geriatric patients. METHODS: A total of 374 patients (140 male, 234 female) aged ≥65 years were included. Comprehensive demographic and clinical data including age, gender, current diagnoses/medications, comorbid diseases and medical problems were noted. ...
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Tags: Aging Clin Exp Res Source Type: research
ConclusionsClinical development appears promising. A phase 2 clinical trial is currently in progress that evaluates the effect of lovastatin lactone on methanogenesis and symptoms in patients with irritable bowel syndrome with constipation. The review concludes with an outlook for the future and subsequent work that needs to be done.
Source: Alimentary Pharmacology and Therapeutics - Category: Drugs & Pharmacology Authors: Tags: Review Article Source Type: research
Over the past two decades, I have watched with increasing alarm the skyrocketing numbers of patients with type 2 diabetes who come to my wellness clinic. Often, they come to see me about other medical issues, but their diabetes adds a new level of complications to their treatment. Type 2 diabetes occurs when the body’s response to insulin – the hormone critical for the maintenance of healthy blood sugar levels – becomes either ineffective or the insulin itself is produced in insufficient amounts. The horrific trend I’m seeing at my wellness clinic mirrors almost exactly what’s happening in the...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Nutrition diabetes insulin statins type 2 diabetes Source Type: news
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