Acylated Ghrelin Protects the Hearts of Rats from Doxorubicin-Induced Fas/FasL Apoptosis by Stimulating SERCA2a Mediated by Activation of PKA and Akt.

In conclusion, AG cardioprotection against DOX involves inhibition of extrinsic cell death and restoring normal Ca+2 homeostasis. PMID: 31093930 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31093930?dopt=Abstract

Source: Cardiovascular Toxicology - May 14, 2019 Category: Cardiology Authors: Shati AA, Dallak M Tags: Cardiovasc Toxicol Source Type: research