Time heals all wounds? A 2-year longitudinal diffusion tensor imaging study in major depressive disorder

Conclusion: This study reports follow-up diffusion tensor imaging data in patients with major depressive disorder after an acute depressive episode. We demonstrated impaired prefrontal white matter microstructure (higher mean diffusivity) at baseline in patients with major depressive disorder, which normalized at follow-up after 2 years, irrespective of disease course. This might have been due to a general treatment effect and might have reflected recovery of white matter integrity. PMID: 31094489 [PubMed - as supplied by publisher]
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research

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ConclusionsThese findings suggest that the psychological well ‐being of parents is an important predictor of maternal and paternal self‐efficacy during toddlerhood. Abortion history was not demonstrated to negatively impact the psychological well‐being of parents with respect to their capacity for parental self‐efficacy.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
CONCLUSION: The experience of physical or sexual abuse may leave detectable structural alterations in key regions of the amygdala, potentially mediating the risk of psychopathology in trauma-exposed youth. PMID: 32940197 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
Conclusions: The position of the eyeball moved in the same direction as the gaze during horizontal gaze, but in the opposite direction during vertical gaze. For accurate eye movement analyses, such as the measurement of the deviation angle in strabismus, translation should be considered in addition to rotation.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
We present the case of a pericaecal hernia treated successfully with a laparoscopic approach and full recovery after surgery. A 53-year-old female patient with a personal history of depression, osteoporosis and irritable bowel syndrome consulted to the emergency department for abdominal pain and distension in the last 12 h, associated with one episode of vomit and diminished frequency in the passage of stools. The right abdomen was tender to palpation, and blood work revealed no leucocytosis. A computed tomography scan showed small bowel loops distended and displaced to the right parietocolic recess, lateral to the ascendi...
Source: Journal of Minimal Access Surgery - Category: Surgery Authors: Source Type: research
ConclusionMiddle-aged people are at significant risk for attempting suicide by jumping from a height in Brazil, independently of gender, with 67.6% deaths. Traumatic brain injury, higher ISS, and more than 3 skeletal injuries are independent variables related to this fatal outcome. Acute complications occur in approximately 50% of survivors. Middle-aged men, foot and ankle injuries, open pelvic injuries, and open fractures are risk factors for complications.
Source: European Journal of Trauma and Emergency Surgery - Category: Emergency Medicine Source Type: research
ConclusionsSupervised group exercise did not improve psychological well ‐being for women with or at high risk of depression at 29‐34 weeks of gestation. Eight weeks postpartum the intervention group reported significantly higher psychological well‐being than the control group. Based on our results, supervised exercise in groups is a safe complementary course of t reatment alongside the existing antenatal care.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
AbstractPresent project is concerned with the possibility to modulate the neural regulation of food intake by non-invasive stimulation of the vagus nerve. This nerve carries viscero-afferent information from the gut and other internal organs and therefore serves an important role in ingestive behavior. The electrical stimulation of the vagus nerve (VNS) is a qualified procedure in the treatment of drug-resistant epilepsy and depression. Since weight loss is a known common side effect of VNS treatment in patients with implanted devices, VNS is evaluated as a treatment of obesity. To investigate potential VNS-related changes...
Source: Brain Imaging and Behavior - Category: Neurology Source Type: research
Analyst, 2020, Accepted Manuscript DOI: 10.1039/D0AN01406K, PaperKelly Elizabeth Dunham, B. Jill Venton Serotonin is a neuromodulator implicated in depression that is often measured in real-time by fast-scan cyclic voltammetry (FSCV). A specialized “Jackson” waveform (JW, 0.2, 1.0 V, -0.1 V, 0.2 V,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
In this study, we address this issue via diffusion tensor imaging (DTI). Twenty-two trauma-exposed individuals who did not meet post-traumatic stress disorder (PTSD) diagnostic criteria were recruited from the most affected area of Wenchuan earthquake and scanned twice (within twenty-five days and two years after the quake, respectively). Their emotional distress was evaluated with the Self-Rating Anxiety/Depression Scales (SAS/SDS) at both scans. Automatic fiber quantification was used to examine brain microstructure alterations. Correlation analyses were also conducted to investigate relationships between brain microstru...
Source: Brain Imaging and Behavior - Category: Neurology Source Type: research
Imagine being in pain and having your doctor tell you it’s all in your head. Unfortunately, this is not an uncommon experience for many of the six million Americans living with fibromyalgia, a chronic, painful condition. People with fibromyalgia experience widespread pain, aches, and stiffness in muscles and joints throughout the body, as well as unusual tiredness. No one knows what causes this condition, and no apparent physical cause has been identified thus far. The most likely culprit is a brain malfunction that amplifies normal nerve responses, causing people with fibromyalgia to experience pain or other symptom...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Bones and joints Fatigue Health Pain Management Source Type: blogs
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