Initial biological evaluations of 18 F-KS1, a novel ascorbate derivative to image oxidative stress in cancer

ConclusionThis work demonstrates the strong preliminary support of18F-KS1, both in vitro and in vivo for imaging ROS in cancer. If successful, this work will provide a new paradigm to directly probe real-time oxidative stress levels in vivo. Our work could enhance precision medicine approaches to treat cancer, as well as neurodegenerative and cardiovascular diseases affected by ROS.
Source: EJNMMI Research - Category: Radiology Source Type: research