Pyruvate responsiveness based on α-oxohydrazone formation for intracellular siRNA release from polyion complex (PIC)-based carriers.

This study provides the rationale for a smart design of pyruvate-responsive materials in the cell, based on α-oxohydrazone formation.
PMID: 31091092 [PubMed - as supplied by publisher]

Source: Biomacromolecules - May 14, 2019 Category: Biochemistry Authors: Takemoto H, Wang CL, Nomoto T, Matsui M, Tomoda K, Nishiyama N Tags: Biomacromolecules Source Type: research