Mono- and poly-functional T cells in nontuberculous mycobacteria lung disease patients: Implications in analyzing risk of disease progression.

CONCLUSIONS: The patients with MAC/MAB-LD had attenuated poly-functional T cells. The triple-positive CD4+ cells could be useful in diagnosing disease from colonization. MAC-specific mono-IFN-γ+ CD4+ cells and triple positive-CD4+ might predict radiographic progression, which could be useful in making treatment decisions.
PMID: 31085455 [PubMed - as supplied by publisher]

Source: Cytokine - May 10, 2019 Category: Molecular Biology Authors: Shu CC, Wu LS, Wu MF, Lai HC, Wang PH, Cheng SL, Wang JY, Yu CJ Tags: Cytokine Source Type: research