Evaluation of risk factors for colistin resistance among uropathogenic isolates of Escherichia coli and Klebsiella pneumoniae: a case-control study.

CONCLUSIONS: K. pneumoniae show six times higher prevalence of colistin resistance than E. coli, and the emergence of resistant organisms has led to an increase in morbidity in infected patients. PMID: 31084700 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research

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As the infections become increasingly resistant to antibiotics, some standard treatments no longer work for an ailment that was once easily cured.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Antibiotics Drug Resistance (Microbial) Infections Research Women and Girls Urinary Tract E Coli (Bacteria) your-feed-science your-feed-health Source Type: news
CONCLUSION: The recognition of E. coli captured by phagosomes or partially damaged by lysosomal attack within the cell was recorded for the first time. Furthermore, SEM observation was performed on human tissue. PMID: 31298302 [PubMed - as supplied by publisher]
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
Age is a significant risk factor for recurrent urinary tract (rUTI) infections, but the clinical picture is often confused in older patients who also present with asymptomatic bacteriuria (ASB). Yet, how bacte...
Source: Immunity and Aging - Category: Geriatrics Authors: Tags: Research Source Type: research
Abstract The NLRP3 inflammasome, IL-1β release and pyroptosis (cell lysis) have recently been proposed to be essential for the progression of urinary tract infection (UTI) and elimination of intracellular bacterial niches. However, the effects of IL-1R antagonist (IL-1RA) on immune responses during UTI, except for its ability to disrupt IL-1β signalling, are not well understood. The aim of this study was to investigate the role of IL-1RA in UPEC colonization of bladder epithelial cells and the subsequent host inflammatory response. Human bladder epithelial cells (5637) and CRISPR/Cas9 generated NLRP3 and...
Source: Cytokine - Category: Molecular Biology Authors: Tags: Cytokine Source Type: research
AbstractRetraction: Nielsen, KL, Hansen, KH, Knudsen, JD, Frimodt ‐Møller, N, Hertz, FB, Jansåker, F., In vivo mecillinam resistance in Escherichia coli after pivmecillinam treatment of a urinary tract infection, MicrobiologyOpen, 2019; e770 (https://doi.org/10.1002/mbo3.770). The above article, published online on 6 January 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors and John Wiley&Sons Ltd. The retraction has been agreed due to the authors ’ self‐reported errors in their data rendering the article’s conclusions incorrect.
Source: MicrobiologyOpen - Category: Microbiology Tags: THIS ARTICLE HAS BEEN RETRACTED Source Type: research
ConclusionsThis first detection of rmtG in E. hormaechei reinforces the ability to horizontal transfer. Location in complex genetic platforms carried by Tn3 transposons in IncA/C plasmids may facilitate dissemination to other Gram-negative pathogens and further limit the treatment options.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
CONCLUSION: The frequencies of urinary tract infection were similar in both groups. These individuals might have been taking non-prescribed antibiotics or failing to comply with a prescribed treatment or bacteria are of hospital origin. PMID: 31260553 [PubMed - in process]
Source: Puerto Rico Health Sciences Journal - Category: International Medicine & Public Health Tags: P R Health Sci J Source Type: research
Publication date: Available online 28 June 2019Source: LWTAuthor(s): Sun Ae Kim, Hye Won Kim, Min Suk RheeAbstractCranberry has been widely utilized as a popular botanical dietary supplement to prevent urinary tract infection. The study aims to evaluate the enhanced bactericidal activities of cranberry against uropathogenic Escherichia coli (UPEC) by adding a small quantity of naturally derived antimicrobials. The antibacterial effect was examined with cranberry extract alone (15 and 20%), three kinds of medium-chain fatty acids alone (caprylic, capric, and lauric acid; 0.05–1.0 mM), essential oils alone (carvacrol...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
CONCLUSIONS: Most of the E. coli virulence genes investigated in this study were observed in E. coli isolates from UTI patients. Virulence genes are very important for the establishment and maintenance of infection.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
CONCLUSIONS: Most of the E. coli virulence genes investigated in this study were observed in E. coli isolates from UTI patients. Virulence genes are very important for the establishment and maintenance of infection.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
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