The separate and combined effects of KCa and KATP channel blockade with NOS inhibition on cutaneous vasodilation and sweating in older men during heat stress.
CONCLUSION: In habitually active older men, blockade of KCa and KATP channels attenuates cutaneous vasodilation during rest and exercise in the heat, respectively, and these effects are NOS-dependent. Furthermore, combined NOS inhibition and KCa channel blockade attenuates sweating during exercise in the heat.
PMID: 31091157 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - Category: Physiology Authors: McGarr GW, Fujii N, Muia CM, Nishiyasu T, Kenny GP Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research