ASAP Diketopiperazine-Type Alkaloids from a Deep-Sea-Derived Aspergillus puniceus Fungus and Their Effects on Liver X Receptor a

Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b00055
Source: Journal of Natural Products - Category: Biochemistry Authors: Source Type: research

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This study covers fabrication and characterization of thymol-loaded nanofiber (TLNs) mats and evaluation of their potential to be used as novel antimould surface coating material for limitation of mould development of Aspergillus parasiticus on kashar cheese surface. Different ratios of polyvinyl alcohol (PVA)/whey protein (WP) were electrospun to yield cylindrical and fine (⁓370 nm in diameter) polymeric nanofiber mats. The fabricated nanofibers were characterized in terms of their zeta potential, electrical conductivity, molecular, thermal and morphological properties. These results revealed that there were inte...
Source: Food Packaging and Shelf Life - Category: Food Science Source Type: research
In this study, we characterized sirtuin in the white koji fungus, Aspergillus kawachii, to examine their role on regulation of amylolytic enzymes and citric acid productions during the solid-state culture (koji). Characterization of rice-koji made using five putative sirtuin gene disruptants indicated that they are involved in amylolytic activity and acidity of rice koji; especially the sirD disruptant showed lower levels of α-amylase activity and citric acid production per mycelial weight in the koji compared the control strain. In addition, the sirD disruptant also showed a change in mycelial pigmentation, higher s...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Aspergillus kawachii Source Type: research
Publication date: Available online 13 June 2019Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Yasir Mehmood Khan, Hira Munir, Zahid AnwarAbstractUrease is one of the important enzymes secreted by microorganisms in the soil, but can also be produced by microbial fermentation. The present study aimed to explore optimum conditions for maximum urease enzyme production from wheat straw by applying a statistical approach, response surface methodology (RSM), under the solid-state fermentation process. Eight different local strains of Aspergillus niger were screened for the production of urease enzyme. Fermentation ...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: October 2019Source: Protein Expression and Purification, Volume 162Author(s): Ye Ke, Meng-yao Wei, Yu-tong Fu, Yan-mei Zhu, Xuan-lin ZhanAbstractThe Aspergillus niger AS3.350 protease gene (pepD) was successfully cloned and expressed in Pichia pastoris KM71. The rPepD activity was 331.5 U/ml, and the optimum temperature and pH were 45 °C and 8–9 respectively. In addition, enzyme activity was significantly inhibited by PMSF, EDTA, Mg2+, Fe2+ and Zn2+ ions, and stimulated by Ca2+ which selectively bound to the T302 and D323 residues. Mutation in either or both of the residues inhibited rPepD exp...
Source: Protein Expression and Purification - Category: Biochemistry Source Type: research
Publication date: September 2019Source: Phytochemistry, Volume 165Author(s): Changxing Qi, Qun Zhou, Weixi Gao, Mengting Liu, Chunmei Chen, Xiao-Nian Li, Yongji Lai, Yuan Zhou, Dongyan Li, Zhengxi Hu, Hucheng Zhu, Yonghui ZhangAbstractSpiroterreusnoids A–F, six undescribed spiro-dioxolane-containing adducts bearing 3,5-dimethylorsellinic acid-based meroterpenoid and 2,3-butanediol moieties were isolated from the endophytic fungus Aspergillus terreus Thom from Tripterygium wilfordii Hook. f. (Celastraceae). The structures of these adducts were established by spectroscopy, single-crystal X-ray diffraction, and experime...
Source: Phytochemistry - Category: Chemistry Source Type: research
Source: Chemistry of Natural Compounds - Category: Chemistry Source Type: research
Abstract The current climate changes in the form of global warming are one of the leading threats to agricultural crops (including soybean and sunflower). To enable the crops to cope with the heat stress, innovative steps are needed to be taken as soon as possible. Fungal endophytes are known to secrete secondary metabolites that promote the growth of host plants under stress conditions. Therefore, we have isolated endophytic fungus from Euphorbia indica (a wild desert plant) and tested it for plant growth promoting activities. The culture filtrate of the fungal strains exhibited the presence of secondary metaboli...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Aspergillosis threatens endangered kakapo, “the world’s fattest parrot”Fri, 06/14/2019 - 11:40News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Publication date: Available online 13 June 2019Source: MethodsXAuthor(s): Jibrin Ndejiko Mohammed, Wan Rosmiza Zana Wan DagangAbstractThe economy of mass bioflocculant production and its industrial application is couple with the cost of production. The growth medium is the most significant factor that accounts for the production cost. In order to find a substitute for the expensive commercial media mostly the carbon and nitrogen sources used for bioflocculant production, we use chicken viscera as a sole source of nutrient for bioflocculant production. The culture conditions for Aspergillus flavus S44-1 growth and biofloccu...
Source: MethodsX - Category: Science Source Type: research
Conclusion: Pse was demonstrated for the first time as a novel alternative therapy for osteoclast-related bone diseases such as osteoporosis through suppressing ROS level.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
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