Photonuclear production, chemistry, and in vitro evaluation of the theranostic radionuclide 47 Sc

Conclusions47Sc can be produced via the48Ti( γ,p)47Sc reaction and separated from natural Ti targets with a yield and radiochemical purity suitable for radiolabeling of peptides for in vitro studies. The data in this work supports the potential use of eLINACs for studies of photonuclear production of medical radionuclides and the future development of high-intensity eLINAC facilities capable of producing relevant quantities of carrier-free radionuclides currently inaccessible via routine production pathways or limited due to costly enriched targets.
Source: EJNMMI Research - Category: Radiology Source Type: research