Nearly 1 in 10 With MI at Young Age Have Familial Hypercholesterolemia Nearly 1 in 10 With MI at Young Age Have Familial Hypercholesterolemia

Familial hypercholesterolemia (FH) is present in 9% of people who experience a myocardial infarction (MI) at age 50 or younger, most of whom continue to have elevated cholesterol at one-year follow-up, according to new research.Reuters Health Information
Source: Medscape Pathology Headlines - Category: Pathology Tags: Cardiology News Source Type: news

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AbstractPurpose of ReviewThe purpose of this article is to review the basic principles of near-infrared spectroscopy (NIRS) and its contemporary role in intracoronary imaging.Recent FindingsNIRS has been demonstrated to effectively detect culprit lesions in acute coronary syndromes (ACS) and to potentially identify vulnerable plaque. Lipid-rich plaques detected by NIRS are also associated with higher incidence of future adverse cardiac events. Plaques with high lipid content detected by NIRS have been shown to predict periprocedural myocardial infarction during percutaneous coronary intervention (PCI). The beneficial effec...
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research
This study aims to evaluate the incidence of statin use and major adverse cardiovascular events (MACE) post-STEMI in those patients with- and without-SMuRFs.
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: 408 Source Type: research
Cardiovascular risk factors contribute differently to short-term prognosis of acute myocardial infarction (AMI); hypertension and diabetes increase adverse outcomes, whereas hyperlipidemia, smoking, and obesity seem to paradoxically decrease these in post-MI patients. We aimed to investigate whether a simple calculation of conventional risk factors, PARADOCS (Pressure of ARtery elevAtion, Diabetes, Obesity, Cholesterol, Smoking) score, would improve the ability to predict major adverse cardiac and cerebrovascular events (MACCEs) in post-MI patients.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
This study sought to investigate what could be learned from how these men have fared. The men were born in 1925-1928 and similar health-related data from questionnaires, physical examination, and blood samples are available for all surveys. Survival curves over various variable strata were applied to evaluate the impact of individual risk factors and combinations of risk factors on all-cause deaths. At the end of 2018, 118 (16.0%) of the men had reached 90 years of age. Smoking in 1974 was the strongest single risk factor associated with survival, with observed percentages of men reaching 90 years being 26.3, 25.7, ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Farmakis I, Zafeiropoulos S, Kartas A, Boulmpou A, Nevras V, Papadimitriou I, Tampaki A, Vlachou A, Markidis E, Koutsakis A, Ziakas A, Karvounis H, Giannakoulas G Abstract Background: Considering the increasing burden of cardiovascular risk factors and recent advances on the management of acute coronary syndromes (ACS), we studied the epidemiological characteristics and treatment strategies of patients presenting with ACS. We also evaluated the lipid profile and attainment of lipid goals in a 'real world' clinical setting. Methods: This was a substudy of IDEAL-LDL (Motivational interviewing to support low-...
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
DNA tests might identify ‘invisible population’ who are not currently seen as in dangerHundreds of thousands more adults in the UK could benefit from taking statins because their genes put them at high risk of heart disease, research suggests.Speaking on Wednesday at the UK Biobank conference in London, Prof Sir Peter Donnelly, the founder of the company Genomics Plc, warned of an “invisible population” who are not identified as at risk by current screening programmes because their blood pressure and cholesterol do not raise red flags.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Heart disease Health Heart attack Science Society UK news Source Type: news
WEDNESDAY, June 19, 2019 -- Radiation treatment for cancer can damage the heart and blood vessels, increasing the risk for a stroke or heart attack. But a new study suggests cholesterol-lowering drugs can significantly reduce that risk. The...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
We reported that plasma levels of angptl2 are elevated in patients with cardiovascular diseases (CVD), were associated with endothelial dysfunction, and were predictive of major cardiac adverse events and death. Recently, we reported a strong relationship between arterial expression of p21, a cell cycle inhibitor overexpressed in senescent cells and maintaining growth arrest, and circulating levels of angptl2 in atherosclerotic patients. Senescent EC are activated and promote aggregation of leukocytes, the initiating step of atherogenesis. We therefore hypothesized that down-regulation of vascular angptl2, preferentially i...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
FRIDAY, June 14, 2019 -- The majority of young heart attack patients with familial hypercholesterolemia (FH) still have elevated cholesterol levels a year later, according to a study published in the May 21 issue of the Journal of the American...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
nn J Abstract Because of new surgical techniques, advanced monitoring modalities and improvements in perioperative care, perioperative mortality and morbidity have been significantly reduced in the last decades; however, patients still suffer from high perioperative mortality and morbidity, especially those with pre-existing cardiovascular diseases. Not only perioperative myocardial infarction but also myocardial injury after non-cardiac surgery, which presents without clinical symptoms, is associated with an adverse outcome. Patients at risk require particular interdisciplinary attention throughout the perioperat...
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research
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