Scientists Spot Unexpected Player in Fibromyalgia

THURSDAY, May 16, 2019 -- Fibromyalgia is a mysterious and misunderstood illness, but researchers may have uncovered at least one key to the disease's origin: insulin resistance. The new research compared a small group of people with fibromyalgia...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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Abstract Background: Current therapeutic modalities for fibromyalgia (FM) do not provide satisfactory results and new approaches have to be explored. Objectives: To assess efficacy and safety of adding a phytotherapy treatment (Fib-19-01) to the current therapeutic regimen in patients with FM. Methods: Double-blind controlled trial: women with active FM (Fibromyalgia Index Questionnaire FIQ> 40) were randomised to receive Fib-19-01 or a food supplement (FS) undistinguishable from Fib-19-01 or no supplementary treatment (NoST). All continued the conventional therapy throughout the 6 month follow-up. Pr...
Source: Alternative Therapies in Health and Medicine - Category: Complementary Medicine Authors: Tags: Altern Ther Health Med Source Type: research
Publication date: Available online 14 June 2019Source: Brain, Behavior, and ImmunityAuthor(s): Andre F. Carvalho, Brisa S. Fernandes, Andre R. Brunoni
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Abstract Although the life-course concept of risk markers as potential etiological influences is well established in epidemiology, it has not featured in academic publications or clinical practice in the context of chronic widespread pain (CWP) and fibromyalgia syndrome (FMS). Studies of risk markers are required considerations for evaluation of patients and for research because there is no single cause, pathological feature, laboratory finding, or biomarker for CWP or FMS. The early-life risk markers identified by extensive literature review with best evidence for potential causal influence on the development and...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
ccedil;eyler N Abstract OBJECTIVE: To investigate whether the expression of cytokine, nociceptionassociated ion channel, and axon guidance genes in skin cells fibromyalgia syndrome (FMS) patients differs from healthy controls potentially contributing to pain and small fiber degeneration in FMS. METHODS: We prospectively recruited 128 patients and 26 healthy controls. All study participants underwent neurological examination and a skin punch biopsy was obtained from the lateral calf and thigh. Skin samples were processed to histologically determine intraepidermal nerve fiber density (IENFD) and for primary fib...
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research
Authors: Gimigliano F PMID: 31186382 [PubMed - in process]
Source: Journal of Musculoskeletal Neuronal Interactions - Category: Neurology Tags: J Musculoskelet Neuronal Interact Source Type: research
Sensory disturbances in fibromyalgia extend beyond nociception. It has been proposed that imbalance in the mutual competition between painful input and non-painful sensory activity may, to a significant extent...
Source: Arthritis Research and Therapy - Category: Rheumatology Authors: Tags: Research article Source Type: research
PMID: 31207336 [PubMed - as supplied by publisher]
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Tags: Brain Behav Immun Source Type: research
This article presents a retrospective analysis of patients who attended a rheumatology specialist practice (with two specialist rheumatologists) between 2016 and 2018 via an appointment arranged by the appointment service office (Terminservicestelle, TSS). Patients were analyzed in a pseudonymized manner and categorized according to the following criteria: 1. patient did not keep the appointment, 2. patient had no inflammatory rheumatic disease, 3. patient suffered from an inflammatory rheumatic disease but had no urgent indications to be seen and 4. patient suffered from an inflammatory rheum...
Source: Zeitschrift fur Rheumatologie - Category: Rheumatology Authors: Tags: Z Rheumatol Source Type: research
Publication date: Available online 12 June 2019Source: Best Practice &Research Clinical RheumatologyAuthor(s): Martin DiersAbstractIn this chapter, we provide an overview of neuroimaging studies in chronic pain. We start with an introduction about the phenomenology of pain. In the following section, the application of functional and structural imaging techniques is shown in selected chronic pain syndromes (chronic back pain, fibromyalgia syndrome (FMS), phantom limb pain, and complex regional pain syndrome (CRPS)), and commonalities and peculiarities of imaging correlates across different types of chronic pain are disc...
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research
Lower back and leg pain can result from poor posture and overstraining the back muscles. However, persistent or recurring pain can be a sign of an underlying condition, such as arthritis or fibromyalgia. Learn more about the possible causes of lower back and leg pain here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Back Pain Source Type: news
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