Atopic Patients Show Increased Interleukin 4 Plasma Levels but the Degree of Elevation Is Not Sufficient to Upregulate Interleukin-4-Sensitive Genes
Conclusion: Our data suggest that the IL-4 plasma levels of atopic patients are not high enough to impact the expression of IL-4-sensitive genes.Skin Pharmacol Physiol
Staphylococcus aureus has been implicated in the pathophysiology of eczema, allergic rhinitis, asthma, and food allergy. S aureus is a marker of more severe eczema, which is a risk factor for food sensitization/allergy. Therefore it might be that the association between S aureus and food allergy in eczematous patients is related to eczema severity.
Abstract BACKGROUND: Not all rhinitis patients are affected by an immunoglobulin E (IgE)-mediated inflammatory process. Skin and serum allergy assessments are limited in their ability to define local allergic rhinitis (LAR). Thus, patients with negative systemic allergy assessments comprise a mix of those who truly have nonallergic rhinitis (NAR) and patients with LAR. OBJECTIVE: To determine the clinical characteristics of patients with NAR. METHODS: A cross-sectional study was performed on consecutive adults with rhinitis symptoms who underwent turbinate surgery. NAR patients were defined by excluding ...
Publication date: Available online 8 May 2019Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Chih-Yung Chiu, Chia-Hsuan Yang, Kuan-Wen Su, Ming-Han Tsai, Man-Chin Hua, Sui-Ling Liao, Shen-Hao Lai, Li-Chen Chen, Kuo-Wei Yeh, Jing-Long HuangAbstractBackgroundAtopic eczema and food allergy most commonly occur in the early childhood. However, the relationships between eczema onset and their relevance to the occurrence of atopic diseases relating to allergen sensitization remain unclear.MethodsWe investigated 186 children who were followed up regularly at the clinic for 4 years in a birth cohort study. The c...
ConclusionsThis study revealed a high frequency of relevant comorbidities and that a substantial proportion of patients have late-onset asthma; all these features define specific different disease phenotypes. Severe asthma complexity and comorbidities require multidisciplinary approaches, led by specifically trained pulmonologists and allergists.
Abstract BACKGROUND: Atopic eczema and food allergy most commonly occur in the early childhood. However, the relationships between eczema onset and their relevance to the occurrence of atopic diseases relating to allergen sensitization remain unclear. METHODS: We investigated 186 children who were followed up regularly at the clinic for 4 years in a birth cohort study. The children were classified into three groups: early-onset eczema (
Little is known about the prevalence of asthma, allergic rhinitis, eczema and allergies among Canadian Inuit children, especially those living in the arctic and subarctic areas.
Conclusions: In asthma and allergy, multimorbidity and polypharmacy are major concerns. Disease severity, drug use, and costs increased with multimorbid conditions. To reduce the burden, allergy management should be better integrated and more comprehensive.Int Arch Allergy Immunol
Conclusions: Our study suggests that there is no association between hs-CRP levels and any of the allergic endpoints in German adolescents. However, whether allergic diseases are inflammatory conditions and which markers might be most sensitive, remain to be confirmed in future studies.Int Arch Allergy Immunol
Condition: Allergic Diseases Intervention: Diagnostic Test: Physician diagnoses a history of asthma or eczema or allergic rhinitis or health pregnant women Sponsor: China Medical University Hospital Recruiting
The clinically observed progression of atopic diseases is often described in terms of an ‘atopic march’; from atopic eczema to respiratory allergies (allergic rhinitis and/or asthma)1-5. The incidence of atopic manifestations has previously been defined by using the first date of hospital admission for these conditions or dispensed prescription of specific medication6 or by the age at diagnoses of atopic manifestations7.