Incidence of pulmonary and venous thromboembolism in pregnancies after in vitro fertilisation: cross sectional study

Source: BMJ Area: News The British Medical Journal has featured a cross-sectional study aimed at estimating the risk of pulmonary embolism and venous thromboembolism in pregnant women after in vitro fertilisation (IVF).   Data from 23,498 women who had given birth after IVF between 1990 and 2008 (in Sweden), and 116,960 individually matched women with natural pregnancies were evaluated. The primary outcomes assessed were risk of pulmonary embolism and venous thromboembolism (identified by linkage to the Swedish national patient register) during the whole pregnancy and by trimester. The researchers reported that:   . Venous thromboembolism occurred in 4.2/1000 women (n=99) after IVF compared with 2.5/1000 (n=291) in women with natural pregnancies (hazard ratio 1.77, 95% confidence interval 1.41 to 2.23). . The risk was particularly increased during the first trimester, at 1.5/1000 after IVF versus 0.3/1000 (hazard ratio 4.22, 2.46 to 7.26). . The proportion of ...
Source: NeLM - News - Category: Drugs & Pharmacology Source Type: news

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Authors: Sucker C Abstract Venous thromboembolisms and pulmonary embolisms are one of the main causes of morbidity and mortality in pregnancy. The increased risk of thrombotic events caused by the physiological changes during pregnancy alone does not justify any medical antithrombotic prophylaxis. However, if there are also other risk factors such as a history of thromboses, hormonal stimulation as part of fertility treatment, thrombophilia, increased age of the pregnant woman, severe obesity or predisposing concomitant illnesses, the risk of thrombosis should be re-evaluated - if possible by a coagulation speciali...
Source: Geburtshilfe und Frauenheilkunde - Category: OBGYN Tags: Geburtshilfe Frauenheilkd Source Type: research
Conditions:   Pulmonary Embolism;   Pregnancy Related;   Venous Thromboembolism Intervention:   Diagnostic Test: OPTICA CTPA Protocol Sponsors:   University College Dublin;   Mater Misericordiae University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Pulmonary Embolism;   Pregnancy Related;   Venous Thromboembolism Intervention:   Diagnostic Test: OPTICA CTPA Protocol Sponsors:   University College Dublin;   Mater Misericordiae University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Pulmonary Embolism;   Pregnancy Related;   Venous Thromboembolism Intervention:   Diagnostic Test: OPTICA CTPA Protocol Sponsors:   University College Dublin;   Mater Misericordiae University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Pulmonary Embolism;   Pregnancy Related;   Venous Thromboembolism Intervention:   Diagnostic Test: OPTICA CTPA Protocol Sponsors:   University College Dublin;   Mater Misericordiae University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Pulmonary Embolism;   Pregnancy Related;   Venous Thromboembolism Intervention:   Diagnostic Test: OPTICA CTPA Protocol Sponsors:   University College Dublin;   Mater Misericordiae University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Pulmonary Embolism;   Pregnancy Related;   Venous Thromboembolism Intervention:   Diagnostic Test: OPTICA CTPA Protocol Sponsors:   University College Dublin;   Mater Misericordiae University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: Chinese women had a substantially lower risk of venous thromboembolism during pregnancy and the postpartum period compared to that of Caucasians. The occurrence of pregnancy-related venous thromboembolism was largely confined to the early pregnancy period, probably related to the adoption of thromboprophylaxis, a lower rate of Cesarean section, and early mobilization. PMID: 31730677 [PubMed]
Source: Blood Research - Category: Hematology Tags: Blood Res Source Type: research
We present the case report of a 26-year-old woman who became pregnant following the successful treatment of severe CTEPH by utilizing BPA. We conclude that patients undergoing effective BPA for CTEPH can consider becoming pregnant if followed closely by a multidisciplinary team, including experts in thrombosis, pulmonary hypertension and obstetrics.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
This study used a descriptive phenomenological approach to explore the lived experience of women diagnosed with VTE in pregnancy and the perinatal period. The study setting was a London, university affiliated hospital. The sample consisted of nine women with deep vein thrombosis or pulmonary embolism in pregnancy or up to six weeks post-partum, diagnosed in the last two years. Semi-structured interviews were undertaken using an interview guide. Interviews were transcribed and analysed using phenomenological descriptive analysis.
Source: Thrombosis Research - Category: Hematology Authors: Tags: Full Length Article Source Type: research
More News: Drugs & Pharmacology | IVF (in vitro fertilisation) | Pregnancy | Pulmonary Thromboembolism | Study | Thrombosis | Women