Reduction of relative handgrip strength and cardiometabolic risk in individuals with HIV/AIDS

CONCLUSIONS: The prevalence of low HS was high and associated with increased WC.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research

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In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: In the largest cohort to date of PLWH and confirmed COVID-19, almost all had a comorbidity associated with severe disease, highlighting the importance of non-HIV risk factors in this population. The racial disparities and frequent link to congregate settings in PLWH and COVID-19 need to be explored urgently.
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE: SPECIAL SECTION: COVID-19 AMONG PEOPLE LIVING WITH HIV Source Type: research
Douglas Brooks served as the head of the White House Office of National AIDS Policy during the Obama Administration as the first openly gay, HIV-positive African American to hold the job. He focused on addressing the health needs of those at higher risk of HIV infection, and is now executive director of community engagement at the biopharmaceutical company Gilead Sciences. Dr. Otis Brawley was chief medical and scientific officer of the American Cancer Society before becoming a professor of oncology at Johns Hopkins, where he oversees a research effort exploring disparities in cancer rates and outcomes. Over a Zoom call, t...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized feature Magazine Source Type: news
Purpose of review To provide aids to deal with increasing amount of several comorbidities in nonoperating room anesthesia (NORA). Recent findings New indexes for assessment of comorbidities are described and guidelines for the care of patients with obesity, obstructive sleep apnea, chronic obstructive pulmonary disease (COPD), diabetes and COVID19 in NORA summarized. Summary In addition to ASA classification, such instruments as Charlson Comorbidity Index, Frailty Index, Surgical Complexity Score and Revised Cardiac Risk could supplement the prospective assessment of the risk of comorbidities. Using institutional p...
Source: Current Opinion in Anaesthesiology - Category: Anesthesiology Tags: NONOPERATING ROOM ANESTHESIA: Edited by Janusz C. Andres Source Type: research
AbstractThis systematic review summarizes the evidence on the earliest patients with COVID-19-HIV co-infection. We searched PubMed, Scopus, Web of Science, Embase, preprint databases, and Google Scholar from December 01, 2019, to June 1, 2020. From an initial 547 publications and 75 reports, 25 studies provided specific information on COVID-19 patients living with HIV. Studies described 252 patients, 80.9% were male, the mean age was 52.7  years, and 98% were on antiretroviral treatment (ART). Co-morbidities in addition to HIV and COVID-19 (multimorbidity) included hypertension (39.3%), obesity or hyperlipidemia (19.3...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, metabolomics is a promising approach for the assessment of biological age and appears complementary to established epigenetic clocks. Sedentary Behavior Raises the Risk of Cancer Mortality https://www.fightaging.org/archives/2020/06/sedentary-behavior-raises-the-risk-of-cancer-mortality/ Living a sedentary lifestyle is known to be harmful to long term health, raising the risk of age-related disease and mortality. Researchers here show that a sedentary life specifically increases cancer mortality, and does so independently of other factors. This is one of many, many reasons to maintain a re...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Abstract INTRODUCTION: The global prevalence of metabolic syndrome (MS) among people living with HIV/AIDS varies from 20% to 33%. OBJECTIVE: to estimate the prevalence of metabolic syndrome and associated factors in a group of HIV-infected patients on antiretroviral therapy. METHODS: This is a cross-sectional study with HIV-infected patients from a reference center in Bahia, Brazil. We evaluated clinical, socio-demographic and anthropometric data. MS was defined according to the guidelines of International Diabetes Federation. RESULTS: We evaluated 152 patients with mean age of 47.3±11.6 year...
Source: Current HIV Research - Category: Infectious Diseases Authors: Tags: Curr HIV Res Source Type: research
Contrast-enhanced ultrasound scans revealed patterns in the lung not typically...Read more on AuntMinnie.comRelated Reading: Use CTA to evaluate obese COVID-19 patients for PE risk Ultrasound scoring aids COVID-19 decisions COVID-19 can be seen on CT scans outside the chest Brain images may show 'cytokine storm' from COVID-19 Lung ultrasound identifies patients with COVID-19
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Conclusion: These results suggest that the ART regimens studied have a comparable effect on overweight/obesity and that the duration of exposure does not affect the outcome. This study calls for further research to elucidate the relative contribution of various factors to BMI change among recipients, including ART regimens. PMID: 32395339 [PubMed]
Source: AIDS Research and Treatment - Category: Infectious Diseases Tags: AIDS Res Treat Source Type: research
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