Reaching For Best Practices in Food Oral Immunotherapy: Report on the Second Annual FAST Meeting.

Reaching For Best Practices in Food Oral Immunotherapy: Report on the Second Annual FAST Meeting. Ann Allergy Asthma Immunol. 2019 May 10;: Authors: Wasserman RL, Jones DH, Windom HH, Meeting Faculty PMID: 31082482 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research

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DiGeorge syndrome (DGS) is a primary immunodeficiency characterized by various degrees of T-cell deficiency. In partial DGS (pDGS), other risk factors could predispose to recurrent infections, autoimmunity, and allergy. The aim of this study was to assess the effect of different factors in the development of infections, autoimmunity, and/or allergy in patients with pDGS. We studied 467 pDGS patients in follow-up at Great Ormond Street Hospital. Using a multivariate approach, we observed that palatal anomalies represent a risk factor for the development of recurrent otitis media with effusion. Gastroesophageal reflux/dyspha...
Source: Blood - Category: Hematology Authors: Tags: Pediatric Hematology, Immunobiology and Immunotherapy Source Type: research
ConclusionsCompared to placebo, AIT with DPAEs is effective in patients with pollen- or HDM-induced rhinoconjunctivitis with or without allergic asthma and improves health-related quality of life. It does not differ significantly in safety and tolerability.
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
Abstract House dust mite (HDM) sublingual immunotherapy (SLIT) in the form of SLIT-tablets is now an established treatment option for HDM allergy and HDM-induced allergic asthma. In SLIT-tablet immunotherapy allergen extracts are formulated as dry tablets and administered under the tongue where it must be solubilized in saliva in order to be able to interact with the immune system of the sublingual mucosa. Solubilization of the extract must occur within a short time span of about one minute after administration, determined by the sublingual holding time recommended by the manufacturer. Currently, two types of HDM ...
Source: Biological and Pharmaceutical Bulletin - Category: Drugs & Pharmacology Authors: Tags: Biol Pharm Bull Source Type: research
Food allergies have a tremendous financial effect on families and society in general, with 8% of families reporting food allergy with a direct medical cost of $4.3 billion.1 Food allergies are also the major risk factor for recurrent emergency department visits for anaphylaxis.2 Therefore, treatment of food allergy and preventing severe reactions are major goals in the allergy community for physicians, patients, and families. One of the major questions in the treatment of food allergy is whether to prescribe oral immunotherapy (OIT).
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Editorial Source Type: research
PMID: 31171236 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
CONCLUSIONS: High-dose SCIT has substantial clinical value in many cat and dog allergic patients. PMID: 31132032 [PubMed - as supplied by publisher]
Source: Journal of Investigational Allergology and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: J Investig Allergol Clin Immunol Source Type: research
Conclusion: These findings may inform clinicians of the strategies for the prevention ofDermatophagoides sensitization and may be of benefit to the future clinical management of allergic diseasesassociated with sensitization toDermatophagoides mites.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - Category: Allergy & Immunology Source Type: research
This report summarizes the opinions of practitioners who had treated more than 7800 patients and outlines the core principles of safe and effective OIT use in clinical practice.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Perspective Source Type: research
This report summarizes the opinions of practitioners who had treated more than 7800 patients and outlines the core principles of safe and effective OIT use in clinical practice.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Perspective Source Type: research
Publication date: May–June 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 5Author(s): Lauren C. Howe, Kari A. Leibowitz, Margaret A. Perry, Julie M. Bitler, Whitney Block, Ted J. Kaptchuk, Kari C. Nadeau, Alia J. CrumBackgroundOral immunotherapy (OIT) can lead to desensitization to food allergens, but patients can experience treatment-related symptoms of allergic reactions that cause anxiety and treatment dropout. Interventions to improve OIT for patients are needed.ObjectiveTo determine whether fostering the mindset that non–life-threatening symptoms during OIT can sig...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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