Intra-tracheal amikacin spray delivery in healthy mechanically ventilated piglets

ConclusionNebulization remains the most reliable and simple technique to deliver inhaled amikacin uniformly to the lung during mechanical ventilation. Further development of tracheal sprays is required to take advantage of potential benefits related to high drug output and low extra-pulmonary deposition in large animals.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research