Altered cytokine expression in Helicobacter pylori infected patients with bleeding duodenal ulcer

Peptic ulcer disease is a condition in which an important role has infection with H. pylori. The most common complication of peptic ulcer is bleeding. The presence of H. pylori triggers local and systemic cytokin...
Source: BMC Research Notes - Category: Research Authors: Tags: Research note Source Type: research

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As a high school junior, I was shown the guts of an implantable defibrillator. That day, I quit my pursuit of a career in medicine to pursue one in medical device design. OK, so my life didn’t go quite that linearly, but many years later I continue to work on life-improving technologies from the consulting side of medical device design. This pursuit continues to be a great passion. The medical device market is in the popular press spotlight these days. Actually, it’s more of a target. Netflix’s documentary The Bleeding Edge explored whether the 510(k) FDA clearance proc...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
ConclusionsThe degree of aspirin effect immediately prior to cardiac surgery was weakly associated with the risks of postoperative bleeding and allogeneic blood product transfusion, suggesting that measuring aspirin-induced antiplatelet effect prior to cardiac surgery may be useful as an adjunct in optimizing patient blood management for patients who are at high-risk of bleeding and requiring allogeneic blood transfusion.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Researchers have developed a new device that could help save lives by picking up internal bleeding earlier during surgery, new research shows.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
Abstract BACKGROUND: This large cohort study aimed to investigate the effect of acquired thrombocytopenia on the prognosis of patients with stable coronary artery disease undergoing percutaneous coronary intervention (PCI). MATERIALS AND METHODS: Patients with stable coronary artery disease undergoing elective PCI were prospectively enrolled during 2013. All patients were followed for a median of 30 months (the 25th and 75th percentiles for follow-up time were 27 and 32 months). After excluding patients with baseline thrombocytopenia (
Source: The American Journal of the Medical Sciences - Category: General Medicine Authors: Tags: Am J Med Sci Source Type: research
DR JOHN SANTANIELLO (Oak Lawn, IL): The CRASH II and MATTERs trials established that tranexamic acid (TXA) benefits patients with hemorrhage in a select cohort, namely, those with fibrinolysis ≥3% on a rapid thrombelastography (TEG). Tranexamic acid did reduce mortality in CRASH II, but it was unclear whether it was due to prevention of clot lysis and improved coagulation with decreased bleeding, because there was no statistical difference in RBC transfusion in those groups. Because TXA inhibits plasmin, it has been speculated that improved survival may be caused by an attenuated inflammatory response by inhibiting its ...
Source: Journal of the American College of Surgeons - Category: Surgery Tags: Western surgical association article Source Type: research
Bleeding is a feared complication of minor oral surgery in patients on treatment with antiplatelet agents and there is no agreed strategy regarding the cessation or not of antiplatelet treatment. The aim of this systematic review was to evaluate bleeding with minor oral surgery in patients on dual antiplatelet therapy (DAPT), single antiplatelet therapy (SAPT), or no antiplatelet therapy (no APT). The PubMed, Embase, Web of Science, and Cochrane Library databases were screened. Sixteen studies were included.
Source: International Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Systematic Review and Meta-Analysis Source Type: research
AbstractBackground and purposeThe National Cardiovascular Data Registry (NCDR) risk scores for mortality, bleeding and acute kidney injury (AKI) are accurate outcome predictors of coronary catheterization procedures in North American populations. However, their application in German clinical practice remained elusive and we thus aimed to verify their use.MethodsNCDR scores for mortality, bleeding and AKI and corresponding clinical outcomes were retrospectively assessed in patients undergoing catheterization for ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI) or fo...
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
AbstractBackgroundTranscatheter aortic valve implantation (TAVI) is emerging as the standard of care for patients with severe aortic stenosis. Recent results have been favourable even for patients with low periprocedural risk.MethodsWe analysed the number of procedures, complications, and in-hospital mortality rates of all patients undergoing isolated aortic valve replacement in 2017 in Germany, focussing especially on transvascular (TV) TAVI. Patients were stratified according the German Aortic Valve Score (AKL) into the risk classes low, intermediate, high and very high ( ≥ 10%).ResultsA total of 17,956 TV-TAVI...
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
AbstractIntroductionStop the Bleed (STB) program was launched by the White House, for the use of bleeding control techniques at the scene of traumatic injury. The purpose of this study was to conduct an STB course in private security and law enforcement personnel.MethodsPre- and post-questionnaire using the Likert scale was shared with participants on their knowledge and comfort level with the use of tourniquets. Participants were also observed while placing tourniquets and the time for placement recorded. The didactic portion and practical session of the STB was then taught and participants were again observed placing tou...
Source: European Journal of Trauma and Emergency Surgery - Category: Emergency Medicine Source Type: research
Microvascular anastomosis of vessels that differ in diameter can be technically difficult and time-consuming. Difficulties with positioning may lead to kinking or compression, and bleeding at the anastomosis can be a problem. Turbulence and sluggish flow in dilated vessels can predispose to thrombosis.1
Source: The British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Short communication Source Type: research
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