Comparison of Contrast-Enhanced Mammography With Conventional Digital Mammography in Breast Cancer Screening: A Pilot Study

Publication date: Available online 16 May 2019Source: Journal of the American College of RadiologyAuthor(s): Geunwon Kim, Jordana Phillips, Elodia Cole, Alexander Brook, Tejas Mehta, Priscilla Slanetz, Michael D.C. Fishman, Evguenia Karimova, Rashmi Mehta, Parisa Lotfi, Nancy Resteghini, Sean Raj, Vandana DialaniAbstractPurposeTo perform a pilot evaluation of contrast-enhanced mammography (CEM) for screening to determine whether it can improve accuracy and reader confidence in diagnosis.Methods and MaterialsThis institutional review board–approved reader study was comprised of 64 de-identified CEM cases acquired from December 1, 2014, to June 7, 2016, including 48 negative, 5 biopsy-proven benign, and 11 biopsy-proven malignancies. Negative cases were followed for at least 2 years without evidence of cancer. Ten breast imagers of varying experience first rated the low-energy (LE) mammogram and then the CEM examination using BI-RADS categories and a 5-point Likert scale for confidence in diagnosis.ResultsThere were 635 out a total possible 640 complete reader interpretations included in this analysis. The remaining five incomplete interpretations were excluded. Median sensitivity and specificity improved with the addition of CEM (sensitivity: 0.86 [95% confidence interval {CI}:0.74-0.95] versus 1 [95% CI: 0.83-1.00], specificity: 0.85 [95% CI: 0.64-0.94] versus 0.88 [95% CI: 0.80-0.92]). Individual receiver operating characteristic curves showed significant improvement w...
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research

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Publication date: Available online 21 June 2019Source: European Journal of RadiologyAuthor(s): Woo Jung Choi, Hak Hee Kim, Joo Hee Cha, Hee Jung Shin, Eun Young Chae, Ga Young YoonAbstractPurposeTo evaluate the radiologic and clinicopathologic factors in radiologic-pathologic discordance (false-negative results) in breast cancer patients who demonstrate radiologic complete response (rCR) in MR imaging after neoadjuvant chemotherapy (NAC).MethodOur institutional review board approved this retrospective study. We included 209 consecutive patients who showed rCR in MR imaging after NAC. rCR was diagnosed when the original les...
Source: European Journal of Radiology - Category: Radiology Source Type: research
According to this study: Among young women who had varying levels of breast cancer risk, screening ultrasonography in addition to mammography offered modest benefits and high rates of screening harms.
Source: AJN - Category: Nursing Tags: Journal Watch Source Type: research
Magnetic Resonance Imaging detects breast cancer at earlier stages than mammography, according to a  studyrecently published inOncology.Around 15 percent of women with breast cancer were diagnosed despite having no causative hereditary gene mutation but had a family history of breast cancer. To better understand diagnosis rates, researchers from Erasmus University in the Netherlands implemented a randomized controlled trial (FaMRIsc) throughout 12 hospitals in the Netherlands to compare the efficacy of MRI screening against mammography in women with a family history of breast cancer.The study took place between Januar...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
To determine if mammographic features from deep learning networks can be applied in breast cancer to identify groups at interval invasive cancer risk due to masking beyond using traditional breast density meas...
Source: Cancer Imaging - Category: Radiology Authors: Tags: Research article Source Type: research
Date: Thursday, 06 20, 2019; Speaker: Etta Pisano, MD, Professor in Residence of Radiology and PI for TMIST, Harvard Medical School; Worta McCaskill-Stevens, MD, MS, Chief, Community Oncology and Prevention Trails Research Group, Division of Cancer Prevention, NCI; Carolyn D. Runowicz, MD, Executive Associate Dean for Academic Affairs, Professor of OB/GYN, Herbert Wertheim College of Medicine, FIU; Building: Building 45 (Natcher Building); Conference Room A/B; CME Credit; Videocast Event
Source: NIH Calendar of Events - Category: American Health Source Type: events
AbstractPurpose of ReviewBreast cancer incidence and mortality in low- and medium-income countries has increased and is predicted to rise. Late presentation, associated with poor prognosis, is unfortunately common to most of these countries. This review discusses recent studies and offers recommendations to address pertinent issues raised.Recent FindingsLate presentation continues to prevail in many LMICs, worse in sub-Saharan Africa. Socioeconomic and demographic factors play a significant role. The fear of mastectomy is a prominent cause of reluctance to seek treatment. Increasing awareness, clinical breast examination a...
Source: Current Breast Cancer Reports - Category: Cancer & Oncology Source Type: research
MRI finds breast cancer earlier than digital mammography in women with a family...Read more on AuntMinnie.comRelated Reading: Surveillance breast MRI is double-edged sword ISMRM: Personalized breast cancer screening is at hand ISMRM: Breast MRI confirms lymph node response to therapy SMRT: Abbreviated protocol may address barriers to breast MRI screening ARRS: Is follow-up breast MRI OK for BI-RADS 3 cases?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
When should women start getting mammograms to screen for breast cancer? With changing guidelines, it may be difficult to determine the best plan of action. Dr. Amy Degnim, a Mayo Clinic surgeon, says women should know the risks and benefits of mammography, as well as their own risk of breast cancer. That information can help [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
The Tomosynthesis Mammographic Imaging Screening Trial (TMIST) is a randomized breast screening trial that will help researchers learn about the best ways to find breast cancer in women who have no symptoms. It compares two Food and Drug Administration-approved types of digital mammography: standard digital mammography (2-D) with a newer technology called tomosynthesis mammography (3-D). Researchers are doing this trial because they do not know if 3-D mammography is better than 2-D mammography for breast cancer screening.For more information go tohttps://orwh.od.nih.gov/Air date: 6/20/2019 1:00:00 PM
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
Condition:   Breast Cancer Intervention:   Diagnostic Test: Mammography outside official screening Sponsors:   Tartu University Hospital;   University of Tartu;   North Estonia Medical Centre Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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