Have Treatment Studies of Depression Become Even Less Generalizable? Applying the Inclusion and Exclusion Criteria in Placebo-Controlled Antidepressant Efficacy Trials Published over 20 Years to a Clinical Sample

Conclusions: Only a minority of depressed patients seen in clinical practice are likely to be eligible for most AETs. The generalizability of AETs has decreased over time. It is unclear how generalizable the results of AETs are to patients treated in real-world clinical practice.Psychother Psychosom
Source: Psychotherapy and Psychosomatics - Category: Psychiatry & Psychology Source Type: research

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Psychother Psychosom
Source: Psychotherapy and Psychosomatics - Category: Psychiatry & Psychology Source Type: research
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Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized mental health onetime syndication Source Type: news
In this study, combined systems pharmacology strategy and RNA-Seq technology, we uncovered psychotherapeutic effects of LJF. In brief, LJF and its active ingredient luteolin can reversed depressive/anxiety-like behavior in rats exposed to chronic mild stress (CMS), restored abnormal gene expression changes and neurotransmission in the striatum of CMS rats, these effects were mediated through triggering the activation of the HTR2A/PLCγ/ERK/CREB pathway.Graphical abstractThe concrete implementation process of systems pharmacology approach in treating psychiatric disorder with LJF (Lonicerae Japonicae Flos) is described...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Publication date: July–August 2019Source: Brain Stimulation, Volume 12, Issue 4Author(s): Bautista Aviles, Sahóry Jeannette, Lopez Melgar Ricardo
Source: Brain Stimulation - Category: Neurology Source Type: research
Authors: Brugnera A, Carlucci S, Compare A, Tasca GA Abstract Interpersonal problems play a prominent role in the development of binge-eating disorder (BED), so that reducing their intensity may be a key focus of many psychological interventions. In recent years, several interpersonal treatments for BED were developed, which posit that binge-eating arises to manage relational problems. However, few studies have evaluated the prototypical interpersonal problems, and no studies evaluated the longitudinal changes in interpersonal functioning after treatment within this population. We investigated the severity and prot...
Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
You're reading How To Keep Your Job While Dealing With Depression, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. By Suzanne Jessee, Founder and CEO, Anew Era TMS We all need to keep our jobs, right? We have financial obligations, mouths to feed, and working for a living is how we make ends meet. When depression hits, our ability to function on the job can be impacted, even putting our livelihood at risk. So, how should someone battling depression manage the mood disorder while continuing at work? It may s...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured health and fitness psychology self improvement Source Type: blogs
Conditions:   Depression;   Parkinson's Disease Intervention:   Behavioral: Cognitive-behavioral therapy (CBT) Sponsor:   Boston University Charles River Campus Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We examined the strength of the relationship between early response and remission in 82 patients who received naturalistic cognitive-behavior therapy in a private practice setting, and 158 patients who received protocol cognitive therapy in a research setting. We predicted that the relationship between early response and remission would be substantial enough to guide clinical decision making in both samples, and that a simple model of severity at Week 4 of treatment would predict remission as effectively as a more complex change score. Logistic regressions showed that a simple model based on the Week 4 Beck Depression Inve...
Source: Behavior Therapy - Category: Psychiatry & Psychology Authors: Tags: Behav Ther Source Type: research
Conclusions Brief coping-focused psychotherapy added to group education for persons with depression or anxiety complaints seemed more effective in enhancing early work participation compared with additional short-term psychotherapy of standard duration with more extended focus. Clinical recovery rate and decline of comorbid subjective health complaints at 2-year follow-up were also in favour of the brief coping-focused program.
Source: Journal of Occupational Rehabilitation - Category: Rehabilitation Source Type: research
This study explored the meaning of "good outcome" within and beyond the much-used statistical indices of clinical significance in standard outcome research as developed by Jacobson and Truax (1991). Specifically, we examined the experiences of patients mar...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
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