Does obesity affect intraocular pressure during laparoscopic surgery?

This study investigated whether intraocular pressure changes differed according to the body mass index of patients undergoing laparoscopic cholecystectomy. Methods: Thirty obese and 30 non-obese patients (body mass index cutoff point, 30 kg/m2) undergoing laparoscopic cholecystectomy were enrolled. Intraocular pressure was measured at baseline (T1), after induction of anesthesia (T2), 5 min after initiation of mechanical ventilation (T3), 5 min after pneumoperitoneum inflation (T4), 5 min after the patient was placed in the head-up position (T5), 5 min after deflation with the patient in the supine position (T6), and 5 min after extubation with the patient in the 30 degrees upright position (T7). Results: The mean intraocular pressure values of the obese and non-obese groups were similar at T1 (16.60 ± 2.93 and 16.87 ± 2.85 mmHg respectively). In both groups, intraocular pressure decreased following initiation of anesthesia (T2) (p
Source: Arquivos Brasileiros de Oftalmologia - Category: Opthalmology Source Type: research

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In this study, we assessed effects of LPZ on adipocyte differentiation and function by using 3T3-L1 preadipocytes and HFD-induced obesity mice as an in vitro and in vivo model, respectively.Main methodsOil red O staining and intracellular triacylglycerol content were used to determine lipid accumulation. Glucose uptake was performed to measure mature adipocyte function. Expression of adipocyte genes was determined by qRT-PCR and immunoblotting.Key findingsLPZ has dual effects on differentiation of 3T3-L1 cells. At low concentrations, LPZ enhanced adipocyte differentiation via induction of PPARγ and C/EBPα, two ...
Source: Life Sciences - Category: Biology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
CONCLUSIONS The subgroups with increased risk of developing multiple unhealthy behaviors and the most prevalent behaviors were identified. These findings are expected to contribute to the better targeting of health promotion and preventive care. It is worth noting that, for the adoption of healthy lifestyle habits, macro-social and inter-sectoral policies are more effective.RESUMO OBJETIVO Estimar a coocorr ência dos principais fatores de risco para doenças crônicas não transmissíveis em adultos (18 a 59 anos) e idosos ( ≥ 60 anos) residentes nas capitais dos estados brasileiros e Distri...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
Orexins [orexin-A (OXA) and orexin-B (OXB)] are two isoforms of neuropeptides produced by the hypothalamus. The main biological actions of orexins, focused on the central nervous system, are to control the sleep/wake process, appetite and feeding, energy homeostasis, drug addiction, and cognitive processes. These effects are mediated by two G protein-coupled receptor (GPCR) subtypes named OX1R and OX2R. In accordance with the synergic and dynamic relationship between the nervous and immune systems, orexins also have neuroprotective and immuno-regulatory (i.e., anti-inflammatory) properties. The present review gathers recen...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Publication date: Available online 20 October 2019Source: American Heart JournalAuthor(s): Neha J. Pagidipati, Yinggan Zheng, Jennifer B. Green, Darren K. McGuire, Robert J. Mentz, Svati Shah, Pablo Aschner, Tuncay Delibasi, Helena W. Rodbard, Cynthia M. Westerhout, Rury R. Holman, Eric D. Peterson, on behalf of the TECOS Study GroupAbstractBackgroundObesity is a risk factor for type 2 diabetes (T2D) and cardiovascular disease (CVD). Whether obesity affects outcomes among those with T2D and atherosclerotic CVD (ASCVD) remains uncertain. Our objective was to investigate the relationship between body mass index (BMI) and ASC...
Source: American Heart Journal - Category: Cardiology Source Type: research
Condition:   Obesity Intervention:   Diagnostic Test: IL-6, Clusterin, Irisin Level Sponsors:   Rehab Werida;   Tanta University Completed
Source: - Category: Research Source Type: clinical trials
Condition:   Obesity Intervention:   Sponsor:   Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis Completed
Source: - Category: Research Source Type: clinical trials
Conditions:   Dyslipidemias;   Metabolic Syndrome;   Sedentary Behavior;   Obesity;   Blood Pressure Interventions:   Behavioral: Low Volume-High Intensity Interval Training;   Behavioral: Moderate Intensity Continuous Training Sponsors:   Coventry University;   INGESPORT HEALTH AND SPA CONSULTING SL Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Condition:   Child Obesity Intervention:   Behavioral: Sports Readiness Intervention Sponsors:   University of Alabama at Birmingham;   The Birmingham City School System Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Americans consume about 150 pounds of milk and eat nearly 40 pounds of cheese and 20 pounds of ice cream per person per year, according to data from the Department of Agriculture. Yogurt and butter intakes are lower, but growing. But should the dairy we’re consuming be low-fat or full-fat? That debate has become increasingly divisive, and for good reason: not all dairy is created equal. Dairy fat and cardiovascular disease Some of the most substantial dairy research has been done in the context of the Dietary Approaches to Stop Hypertension (DASH) diet, which has been shown, among other benefits, to reduce blood pres...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Cancer Diet and Weight Loss Health Healthy Eating Heart Health Source Type: blogs
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