The need for mathematical modelling of spatial drug distribution within the brain

The blood brain barrier (BBB) is the main barrier that separates the blood from the brain. Because of the BBB, the drug concentration-time profile in the brain may be substantially different from that in the b...

Source: Cerebrospinal Fluid Research - May 16, 2019 Category: Neurology Authors: Esm ée Vendel, Vivi Rottschäfer and Elizabeth C. M. de Lange Tags: Review Source Type: research