Longitudinal impact of dapagliflozin treatment on ventricular repolarization heterogeneity in patients with type 2 diabetes
QTc dispersion (QTcd) tended to be decreased at 24 weeks and was significantly decreased at 2 years after dapagliflozin treatment. In the subgroup with QTcd?53.7 ms (median), QTcd was significantly decreased at 24 weeks and remained improved for 2 years. Dapagliflozin also significantly reduced Tpeak ‐Tend/QT in a subgroup with Tpeak‐Tend/QT?0.25 (median).
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tatsuya Sato,
Takayuki Miki,
Shinya Furukawa,
Bunzo Matsuura,
Yoichi Hiasa,
Hirofumi Ohnishi,
Masaya Tanno,
Tetsuji Miura Tags: Letter to the Editor Source Type: research