Overgrowth Syndrome

Large offspring syndrome (LOS) is a fetal overgrowth condition in bovines most often observed in offspring conceived with the use of assisted reproductive technologies (ART). Phenotypes observed in LOS include, overgrowth, enlarged tongues, umbilical hernias, muscle and skeleton malformations, abnormal organ growth and placental development. Although LOS cases have only been reported to be associated with ART, fetal overgrowth can occur spontaneously in cattle (S-LOS). S-LOS refers to oversized calves that are born at normal gestation lengths. ART-induced LOS has been characterized as an epigenetic syndrome, more specifically, a loss-of-imprinting condition. We propose that S-LOS is also a loss-of-imprinting condition.
Source: Veterinary Clinics of North America: Food Animal Practice - Category: Veterinary Research Authors: Source Type: research

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ConclusionOur study suggests that AF had a significantly improved hernia-specific quality of life in all domains at 30-days postoperatively. We also identified that pain as a binary variable is inadequate for its states purpose. Thus, the overall well-being and morbidity should be taken into account when evaluating hernia patients postoperatively.
Source: Hernia - Category: Sports Medicine Source Type: research
Specialist reserchers detect brain damage in patients with cervical hernias by using neuroimage and artificial intelligence techniques
Source: Disabled World - Category: Disability Tags: Spinal Cord Injury Source Type: news
Condition:   Umbilical Hernia Intervention:   Device: Onlay Mesh group Sponsor:   Maria Melkemichel Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionHartmann ’s reversal remains challenging but can have low complication and mortality rates if performed on selected patients in a reference center. An ASA of 3 was the only predictor of mortality.
Source: Surgery Today - Category: Surgery Source Type: research
CONCLUSION: Morgagni hernias are amenable to minimally invasive repair with this simple technique. With large defects, synthetic patches should be used. Recurrences are rare, and morbidity is low. PMID: 31926567 [PubMed - in process]
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
ConclusionThe use of CST versus No-CST in the repair of large VHs results in an increased risk of wound complications but does not increase the hernia recurrence rate. In the largest QOL comparative study to date, CST ’s generation of myofascial advancement flaps does not negatively impact patient QOL in the repair of large ventral hernias in the short or long term.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
AbstractPurposeThere is increasing emphasis on value in health care, defined as quality over cost required to deliver care. We analyzed outcomes and costs of repairing medium-sized ventral hernias to identify whether an open retromuscular or laparoscopic intraperitoneal onlay approach would provide superior value to the patient and healthcare system.MethodsA retrospective analysis of prospectively collected data from the Americas Hernia Society Quality Collaborative was performed for patients undergoing clean, elective repair of ventral hernias between 4 and 8  cm in width at our institution between 4/2013 and 12/2016...
Source: Hernia - Category: Sports Medicine Source Type: research
Condition:   Hernia, Ventral Interventions:   Procedure: Incisional hernia repair by the mesh implant in sublay retromusuclar position;   Procedure: Incisional hernia repair by the mesh implant in sublay retromusuclar position with using a local hemostatic Hemoblock Sponsor:   Nijznevartovsk County Clinical Hospital Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: An open PP-VHR is a very effective means to repair large, complex, and recurrent hernias resulting in a low recurrence rate. Mesh choice in VHR is important and was associated with hernia recurrence and wound complications in this population.
Source: Annals of Surgery - Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research
ConclusionsThere was no difference in the incidence of IHR after open compared to laparoscopic resection. Compared to the open approach, laparoscopic resection increased the rate of subsequent emergency IHR, suggesting that a more aggressive therapeutic approach may be warranted in this patient group upon diagnosis of an incisional hernia.
Source: World Journal of Surgery - Category: Surgery Source Type: research
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