World Health Organization (WHO) issues guideline on prevention of dementia

The WHO has published its first guideline on the prevention and management of dementia, recommending the adoption of specific lifestyle interventions such as encouraging physical activity and smoking cessation for reducing the risk of cognitive decline and dementia.
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“We have a lot of history to show off here, so it's a great way for individuals to tap into their senses to help recall memories.” ... You are leaving and going to the website of our trust...
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Authors: Li H, Habes M, Wolk DA, Fan Y, Alzheimer's Disease Neuroimaging Initiative and the Australian Imaging Biomarkers and Lifestyle Study of Aging Abstract INTRODUCTION: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. METHODS: A deep learning method is developed and validated based on magnetic resonance imaging scans of 2146 subjects (803 for training and 1343 for validation) to predict MCI subjects' progression to AD dementia in a time-to-event analysis setting. RESUL...
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Authors: Strandberg TE, Tienari PJ PMID: 31201097 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
In this study, analysis of antioxidant defense was performed on the blood samples from 184 "aged" individuals aged 65-90+ years, and compared to the blood samples of 37 individuals just about at the beginning of aging, aged 55-59 years. Statistically significant decreases of Zn,Cu-superoxide dismutase (SOD-1), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were observed in elderly people in comparison with the control group. Moreover, an inverse correlation between the activities of SOD-1, CAT, and GSH-Px and the age of the examined persons was found. No age-related changes in glutathione reductas...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
My father developed instant dementia because of a failed brain surgery. The irony, of course, was that this surgery was supposed to correct the results of a World War II brain injury and prevent the possibility of dementia. This abrupt change was devastating to my family and very difficult for us to accept. One day he was my dad. He was growing older and frailer, of course, but he was still Dad. After he came out of surgery, he was a man plagued by paranoia and hallucinations; a man who had no way of differentiating between our reality and the warped version his brain created. Read more on Agingcare about  the struggl...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
BONNIE ESTRIDGE: A few weeks ago, a bus stop appeared slap bang in the middle of the dementia ward at my local hospital, St George's in London. There it was, complete with the iconic red circle.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conclusion: Evaluations of person-centred practice in rehabilitation for people living with dementia in peer-reviewed literature are lacking. Evaluations are needed to identify effective strategies to pursue and uphold person-centred care. Given the dearth of research on evaluations of person-centredness in rehabilitation, this article included research in person-centred dementia care in the discussion, which potentially can inspire practice and research of rehabilitation for people living with dementia. To understand the complex nature of person-centredness, a variety of research methodologies of qualitative and quantitat...
Source: Journal of Aging Research - Category: Geriatrics Tags: J Aging Res Source Type: research
In this study, the efficiency of collecting the essential oil using steam distillation of the volatile substance was disclosed The active principles were explored, and four sesquiterpenoids and five monoterpenoids were revealed as active principles against β-secretase; On the other hand, α-turmerone, β-turmerone and ar-turmerone were also investigated in a pharmacokinetic absorption experiment. After oral administration, these compounds were detected in an intact form in the brain and serum. These results suggest that consumption of-turieric constituents may prevent dementia. PMID: 30508333 [PubMed - indexed for MEDLINE]
Source: Natural Product Communications - Category: Biochemistry Tags: Nat Prod Commun Source Type: research
ConclusionsOlder age, history of atrial fibrillation and pneumonia are associated with increased risk of influenza-associated in-hospital and 90-day mortality. Statin use may decrease 90-day mortality.
Source: Infection - Category: Infectious Diseases Source Type: research
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