Less fat, more fruit may cut risk of dying of breast cancer

A large experiment finds that trimming dietary fat and eating more fruits and vegetables may lower a woman's risk of dying of breast cancer
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news

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Publication date: Available online 24 May 2019Source: Pathology - Research and PracticeAuthor(s): Ligang Niu, Yuhui Zhou, Wei Zhang, Yu RenAbstractBreast cancer (BC) is one of the primary tumors with high incidence in women. The purpose of this study was to investigate the role of LINC00473 and underlying mechanisms in BC. Expression pattern of LINC00473 was analyzed using qRT-PCR (quantitative real-time polymerase chain reaction) assays in BC tissues and cells. Overexpression or knockdown of LINC00473 in vitro and functional experiments were performed to study its effects on BC cells. Target prediction, luciferase assays,...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 23 May 2019Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Andrei Sakai, Ana Paula de Sousa Mesquista, Erica Valadares de Castro Levatti, Anita Hilda Straus, Helena B. Nader, Carla Cristina Lopes, Luciano CaseliAbstractTrastuzumab (Tmab) is a monoclonal antibody administered as targeted therapy for HER2-positive breast cancer whose molecular interactions at the HER2 receptor microenvironment are not completely clarified yet. This paper describes the influence of Tmab in the molecular organization of films of biological-relevant molecules at the air water interface. Fo...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
Authors: Mayrovitz H Abstract Obesity is linked to the risk of breast cancer and treatment-related lymphedema (BCRL). Thus, knowledge of how obesity, or more specifically total body fat percentage (TBF) and body mass index (BMI), affect measurements that are used to detect or track lymphedema is clinically important. Tissue dielectric constant (TDC) is one measure used to help characterize lymphedema features, detect its presence, and assess treatment-related changes. The goal of this research was to determine the extent to which TDC values depend on TBF and BMI. TDC was measured on both forearms (2.5mm depth) in 2...
Source: Lymphology - Category: Internal Medicine Tags: Lymphology Source Type: research
This study aimed to establish diagnostic accuracy of interlimb differences of ultrasonographic subcutaneous tissue thickness measurements in breast cancer-related arm lymphedema. We compared the truncated cone method by using circumference measurements and interlimb differences of ultrasonographic subcutaneous tissue thickness measurements to evaluate the diagnostic accuracy of interlimb differences of ultrasonographic subcutaneous tissue thickness measurements. Sensitivity, specificity, receiver-operating characteristic (ROC) curve, and area under the curve (AUC) were used. Analysis of ROC curves yielded area under the cu...
Source: Lymphology - Category: Internal Medicine Tags: Lymphology Source Type: research
The FDA approved alpelisib (Piqray, Novartis) to be used with the FDA-approved fulvestrant in certain patients with breast cancer. A companion test was also approved.FDA Approvals
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news
AbstractPurpose of ReviewThe consequence of treatment for gynaecological cancers can cause sudden onset of intense menopausal symptoms, such as vasomotor symptoms, sexual dysfunction and emotional instability. Hormone replacement therapy (HRT) is often effective and can overcome these unpleasant and severe symptoms. However, data regarding its safety remains controversial. The big question therefore is whether HRT in gynaecological cancer survivors is possible. This is due to the fear of disease relapse. So, the purpose of this study was to review the evidence regarding cancer recurrence or death following use of HRT in su...
Source: Current Obstetrics and Gynecology Reports - Category: OBGYN Source Type: research
ConclusionsThe investigative team developed a novel breast cancer treatment DA that is acceptable to women ≥70 years with a history of ER+, HER2-, early stage breast cancer. Next, the DA's efficacy needs to be tested with diverse older women newly diagnosed with breast cancer.
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
May 24, 2019 -- Today, the U.S. Food and Drug Administration approved Piqray (alpelisib) tablets, to be used in combination with the FDA-approved endocrine therapy fulvestrant, to treat postmenopausal women, and men, with hormone receptor...
Source: Drugs.com - New Drug Approvals - Category: Drugs & Pharmacology Source Type: news
The U.S. Food and Drug Administration (FDA) said on Friday that it had approved Novartis AG's treatment in combination with a hormone therapy for postmenopausal women, as well as for men, with a form of advanced breast cancer.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Breast cancer detection is similar with digital breast tomosynthesis (DBT) or standard digital mammography, though DBT may reduce recall rates, researchers say.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
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