Contribution of polymorphonuclear neutrophils in the blood periphery to ischemic brain injury

PMNs abundantly accumulate in ischemic brain tissue in response to stroke both in rodents and human patients, where they massively release enzymes, such as myeloperoxidase and elastase, and reactive oxygen species (ROS), which are known contributors to ischemic injury.1–3
Source: Neurology Neuroimmunology and Neuroinflammation - Category: Neurology Authors: Tags: All Immunology, Infarction Editorial Source Type: research