AHA News: More Clues to the Genetics Behind an Inherited Cholesterol Disorder

WEDNESDAY, May 15, 2019 (American Heart Association News) -- High cholesterol is a risk factor for heart disease, but not all forms of it are the same. An underdiagnosed genetic condition called familial hypercholesterolemia can cause dangerously...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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CONCLUSIONS: The presence of hypercholesterolemia increases the LTR for CHDs in the Japanese population, especially in men. This estimate can be used in preventive knowledge translation efforts at the population level. PMID: 31217364 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
DiscussionHMW adiponectin may be a promising biomarker of cardiometabolic health, especially among PwS. Adiponectin is a potential target for lifestyle and pharmacological interventions. Research on the possible role of HMW adiponectin in modifying cardiometabolic pathology in schizophrenia is needed.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Supplementation not associated with reduced risks of CVD events or all-cause mortality in meta-analysis Related items fromOnMedica Coronary heart disease remains UK ’s biggest killer NICE says far more people should take statins Type 2 diabetes in 10 times more young people than realised Sugar not saturated fat is the major issue for CVD Physical activity might offset harms of time spent sitting
Source: OnMedica Latest News - Category: UK Health Source Type: news
DNA tests might identify ‘invisible population’ who are not currently seen as in dangerHundreds of thousands more adults in the UK could benefit from taking statins because their genes put them at high risk of heart disease, research suggests.Speaking on Wednesday at the UK Biobank conference in London, Prof Sir Peter Donnelly, the founder of the company Genomics Plc, warned of an “invisible population” who are not identified as at risk by current screening programmes because their blood pressure and cholesterol do not raise red flags.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Heart disease Health Heart attack Science Society UK news Source Type: news
Conclusion: Treatment with statins prevents ischemic stroke, especially in patients with high cardiovascular risk and established atherosclerotic disease. It seems that both lipid lowering and pleiotropic effects contribute to these effects. PMID: 31218948 [PubMed - as supplied by publisher]
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research
Authors: Xu Y, Hu H, Li Y, Cen R, Yao C, Ma W, Huang M, Yin Y, Gao H, Liu Y, Endler A Abstract Context: Huoxin formula is a Traditional Chinese Medicine for coronary heart disease (CHD) treatment. Objective: To explore the therapeutic mechanism of the Huoxin formula on arterial functions in CHD patients. Materials and methods: Fifty-eight CHD patients receiving cardiovascular drugs including β-receptor blocker, statins, and antiplatelet medications or others were randomized into intervention [additionally 13.5 g Huoxin formula granules dissolved in 150 mL warm water per time, twice a day (n&thins...
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
CONCLUSIONS: Compared with the nonuse of LT, there may be a hierarchy of residual vascular risk after stroke by non-LDL type and target, while on LT. Particularly, stroke patients with low HDL-C levels on LT may benefit from additional therapeutic strategies to improve their outcomes. PMID: 31189759 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Conclusions for Practice The social ecological model framework suggests that childhood adversity can be considered at multiple levels; that is, a sustainable reduction in the adverse health impacts of childhood adversity requires a concerted effort among policymakers and practitioners that includes both “upstream” and “downstream” approaches.
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
So much time and energy have been wasted these past 40 or so years in trying to reduce dietary fat, including saturated fat. All you need do is look around you to see the result: the most unhealthy, fattest, most diabetic population in history, prescribed more drugs, more reliant on this (corrupt and unhelpful) thing called modern healthcare, with people in healthcare such as your doctor blaming YOU, rather than themselves and their misguided message. After all, doctors and dietitians are following the dictates of the U.S. Dietary Guidelines for Americans and the USDA food plate that carries the blessings of Big Food and a...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Low-fat diet grain-free low-carb undoctored wheat belly Source Type: blogs
ConclusionAs a novel inflammation-based risk score, the CRP/albumin ratio may be an easily accessible marker for assessment of stent restenosis risk.ResumoObjetivoA reestenose de stent permanece como um desafio clínico em doentes com cardiopatia isquémica. A reestenose de stent está associada a intervenções coronárias recorrentes bem como a aumento de internamentos e de custos médicos. A inflamação tem um papel significativo. Embora a associação entre reestenose de stent e o aumento dos níveis de proteína C-reativa (PCR) e a diminui&...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
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